Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498635 | 0.82 | POLB (0.36) | RAB9AKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3688469 | 0.82 | RAB9A (0.42) | RAB9AKMT2ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL1498732 | 0.80 | TDP1 (0.41) | RAB9AKMT2ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL3698112 | 0.79 | ALDH1A1 (0.46) | RAB9AKMT2ASMN1; SMN2NPC1CACNA1B | |
| SCHEMBL1498813 | 0.77 | RAB9A (0.38) | RAB9AKMT2ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL11476717 | 0.76 | JAK3 (0.38) | RAB9AKMT2ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL4492651 | 0.75 | HRH4 (0.38) | RAB9AKMT2ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL1498709 | 0.75 | ABL1 (0.40) | RAB9AKMT2AMEN1EPHX1 | |
| SCHEMBL146034 | 0.73 | IDO1 (0.45) | SMN1; SMN2ALDH1A1ARCYP3A4 | |
| SCHEMBL17845409 | 0.72 | SMN1; SMN2 (0.56) | RAB9AKMT2ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |