Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498732 | 0.84 | TDP1 (0.41) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1498737 | 0.79 | RAB9A (0.36) | ALDH1A1CYP3A4MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL1133820 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL144947 | 0.75 | ALDH1A1 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL11476717 | 0.74 | JAK3 (0.38) | TSHRSMN1; SMN2RAB9AEPHX1LMNA | |
| SCHEMBL11475329 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL3688469 | 0.73 | RAB9A (0.42) | ALDH1A1SMN1; SMN2RAB9AEPHX1LMNA | |
| SCHEMBL4492651 | 0.73 | HRH4 (0.38) | ALDH1A1CYP3A4ALOX15HSD17B10ALOX12 | |
| SCHEMBL4489912 | 0.71 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL8589385 | 0.70 | ALDH1A1 (0.67) | ALDH1A1CYP3A4ALOX15TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |