Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND2 | P30279 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251020 | 1.00 | BRPF1 (0.39) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL1498659 | 0.79 | BRPF1 (0.39) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL5364876 | 0.76 | CDK4 (0.43) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL30250982 | 0.75 | ADORA1 (0.43) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL809908 | 0.74 | LMNA (0.50) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL11286560 | 0.70 | BRPF1 (0.50) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL20975457 | 0.69 | MIF (0.44) | BRPF1BRD4BRD9SLC40A1KDM4E | |
| SCHEMBL29533844 | 0.68 | CCR1 (0.43) | SLC40A1KDM4EPTGER4PIM1PIM2 | |
| SCHEMBL557084 | 0.68 | CCR1 (0.43) | SLC40A1KDM4EPTGER4PIM1PIM2 | |
| SCHEMBL24130871 | 0.67 | NQO2 (0.46) | BRPF1CA12BRD4CA9KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187690-B2 | Rare earth metal complex having phenanthroline compound as ligand | B.R.A.H.M.S. GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9187690-B2 | Rare earth metal complex having phenanthroline compound as ligand | B.R.A.H.M.S. GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9187690-B2 | Rare earth metal complex having phenanthroline compound as ligand | B.R.A.H.M.S. GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| EP-2683725-B1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | BRAHMS GMBH (DE) | 2015-08-26 | — | — | EP | disclosed |
| EP-2683725-B1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | BRAHMS GMBH (DE) | 2015-08-26 | — | — | EP | disclosed |
| EP-2477986-B1 | PHENANTHROLINE DERIVATIVES AND THEIR USE AS LIGANDS | BRAHMS GMBH (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-20140058073-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S. GMBH (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20140058073-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S. GMBH (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20140058073-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S. GMBH (DE) | 2014-02-27 | — | — | US | disclosed |
| US-8648194-B2 | Compounds having phenanthroline structure | B.R.A.H.M.S GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-8648194-B2 | Compounds having phenanthroline structure | B.R.A.H.M.S GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-8648194-B2 | Compounds having phenanthroline structure | B.R.A.H.M.S GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| EP-2683725-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S GmbH (DE) | 2014-01-15 | — | — | EP | disclosed |
| US-20120238748-A1 | NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE | B.R.A.H.M.S GMBH (DE) | 2012-09-20 | — | — | US | disclosed |
| WO-2012124310-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S GMBH (DE) | 2012-09-20 | — | — | WO | disclosed |
| US-20120238748-A1 | NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE | B.R.A.H.M.S GMBH (DE) | 2012-09-20 | — | — | US | disclosed |
| US-20120238748-A1 | NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE | B.R.A.H.M.S GMBH (DE) | 2012-09-20 | — | — | US | disclosed |
| WO-2012124310-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S GMBH (DE) | 2012-09-20 | — | — | WO | disclosed |
| EP-2477986-A1 | PHENANTHROLINE DERIVATIVES AND THEIR USE AS LIGANDS | B.R.A.H.M.S GmbH (DE) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011030566-A1 | PHENANTHROLINE DERIVATIVES AND THEIR USE AS LIGANDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238748-A1 | NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE | PAH, BPTF, HDAC1 | BRPF1 797/4885CA12 1573/4885BRD4 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.