SCHEMBL809908

SCHEMBL809908

Cn1c(=O)ccc2ccc3cccnc3c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
CCR1 P32246 3/20 0.50
CCR5 P51681 3/20 0.50
CCR8 P51685 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
HTT P42858 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MMP2 P08253 2/20 0.50
TSHR P16473 2/20 0.50
GMNN O75496 1/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MMP9 P14780 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
MMP8 P22894 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712289 0.77 BRD4 (0.50) LMNACCR1CCR5CCR8KDM4E
SCHEMBL2614748 0.77 BRD4 (0.50) LMNACCR1CCR5CCR8KDM4E
SCHEMBL1498746 0.74 BRPF1 (0.39) LMNAKDM4EHTTCA12BRD4
SCHEMBL30251020 0.74 BRPF1 (0.39) LMNAKDM4EHTTCA12BRD4
SCHEMBL1498659 0.74 BRPF1 (0.39) KDM4ECA12BRD4BRPF1CA9
SCHEMBL17782974 0.73 PARP1 (0.41) KDM4EMAPTHTTHSP90AA1CA12
Phenanthroline SCHEMBL29405279 0.72 CCR1 (0.94) LMNACCR1CCR5CCR8KDM4E
Phenanthroline SCHEMBL30804600 0.72 CCR1 (0.94) LMNACCR1CCR5CCR8KDM4E
SCHEMBL8559356 0.71 BRPF1 (0.52) KDM4ECA12BRD4BRPF1CA9
Phenanthroline SCHEMBL8845760 0.70 CCR1 (1.00) LMNACCR1CCR5CCR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187690-B2 Rare earth metal complex having phenanthroline compound as ligand B.R.A.H.M.S. GMBH (DE) 2015-11-17 US disclosed
US-9187690-B2 Rare earth metal complex having phenanthroline compound as ligand B.R.A.H.M.S. GMBH (DE) 2015-11-17 US disclosed
US-9187690-B2 Rare earth metal complex having phenanthroline compound as ligand B.R.A.H.M.S. GMBH (DE) 2015-11-17 US disclosed
EP-2683725-B1 RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND BRAHMS GMBH (DE) 2015-08-26 EP disclosed
EP-2683725-B1 RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND BRAHMS GMBH (DE) 2015-08-26 EP disclosed
EP-2477986-B1 PHENANTHROLINE DERIVATIVES AND THEIR USE AS LIGANDS BRAHMS GMBH (DE) 2014-11-12 EP disclosed
US-20140058073-A1 RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND B.R.A.H.M.S. GMBH (DE) 2014-02-27 US disclosed
US-20140058073-A1 RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND B.R.A.H.M.S. GMBH (DE) 2014-02-27 US disclosed
US-20140058073-A1 RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND B.R.A.H.M.S. GMBH (DE) 2014-02-27 US disclosed
US-8648194-B2 Compounds having phenanthroline structure B.R.A.H.M.S GMBH (DE) 2014-02-11 US disclosed
US-20100234548-A1 PHENANTHROLINE-COMPRISING COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2010-09-16 US disclosed
US-20100234548-A1 PHENANTHROLINE-COMPRISING COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2010-09-16 US disclosed
US-20100234548-A1 PHENANTHROLINE-COMPRISING COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2010-09-16 US disclosed
EP-2222724-A1 CATALYST SYTEM FOR OLEFIN POLYMERIZATION COMPRISING PHENANTROLINE-COMPRISING IRON COMPLEXES Basell Polyolefine GmbH (DE) 2010-09-01 EP disclosed
EP-2222722-A1 PHENANTROLINE-COMPRISING COMPLEXES Basell Polyolefine GmbH (DE) 2010-09-01 EP disclosed
WO-2009080236-A1 PHENANTROLINE-COMPRISING COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2009-07-02 WO disclosed
WO-2009080236-A1 PHENANTROLINE-COMPRISING COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2009-07-02 WO disclosed
WO-2009080237-A1 CATALYST SYTEM FOR OLEFIN POLYMERIZATION COMPRISING PHENANTROLINE-COMPRISING IRON COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2009-07-02 WO disclosed
WO-2009080237-A1 CATALYST SYTEM FOR OLEFIN POLYMERIZATION COMPRISING PHENANTROLINE-COMPRISING IRON COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2009-07-02 WO disclosed
EP-1732935-B1 LANTHANIDE CHELATES AND USE THEREOF IN BIOANALYSIS SENSIENT IMAGING TECHNOLOGIES (DE) 2007-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234548-A1 PHENANTHROLINE-COMPRISING COMPLEXES WASF2, BPTF, PICALM LMNA 3350/4885CCR1 2902/4885CCR5 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.