Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 6/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14989099 | 0.90 | AURKB (0.56) | AURKAAURKB | |
| SCHEMBL4308985 | 0.89 | AURKA (0.60) | AURKAAURKBPARP1HTTPDCD1 | |
| SCHEMBL4308994 | 0.89 | AURKA (0.60) | AURKAAURKBPARP1HTTPDCD1 | |
| SCHEMBL14989337 | 0.87 | AURKA (0.49) | AURKAAURKBPDGFRBMAPK10MEN1 | |
| SCHEMBL14989042 | 0.85 | AURKA (0.59) | AURKAAURKBPDGFRBKDRMAPK10 | |
| SCHEMBL14989004 | 0.85 | AURKA (0.58) | AURKAAURKBPDGFRBKDRMAPK10 | |
| SCHEMBL14988985 | 0.85 | AURKA (0.46) | AURKAAURKBHTTKDRMEN1 | |
| SCHEMBL14989290 | 0.84 | AURKB (0.52) | AURKAAURKB | |
| SCHEMBL14989222 | 0.84 | AURKA (0.57) | AURKAAURKBHTTPDGFRBKDR | |
| SCHEMBL14989122 | 0.84 | AURKA (0.57) | AURKAAURKBPARP1PDGFRBMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847532-B1 | IGF-1R INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-06-05 | — | — | EP | claimed |