Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67633 | 0.76 | POLB (0.46) | CYP3A4ALOX15MAOBCYP19A1KDM4E | |
| SCHEMBL10385537 | 0.75 | POLB (0.46) | KDM4EPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL501137 | 0.74 | RET (0.49) | CYP3A4MAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL29963529 | 0.74 | RET (0.49) | CYP3A4MAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL18885280 | 0.74 | CYP19A1 (0.47) | CYP3A4MAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL21371327 | 0.74 | CYP19A1 (0.47) | CYP3A4MAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL16376660 | 0.74 | ESR1 (0.55) | CYP3A4MAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL3965026 | 0.71 | CYP19A1 (0.47) | CYP3A4MAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL1892218 | 0.67 | RET (0.51) | CYP3A4ALOX15MAOBCYP19A1KDM4E | |
| SCHEMBL69674 | 0.67 | CYP19A1 (0.49) | MAOBCYP19A1POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526941-A1 | Anti-inflammatory Modalities | Marshall Edwards, Inc. (US) | 2012-11-28 | — | — | EP | disclosed |
| US-20120059176-A1 | ANTI-INFLAMMATORY MODALITIES | MARSHALL EDWARDS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20090131513-A1 | ANTI-INFLAMMATORY MODALITIES | NOVOGEN RESEARCH PTY LTD. (AU) | 2009-05-21 | — | — | US | disclosed |
| EP-1861090-A1 | ANTI-INFLAMMATORY MODALITIES | Novogen Research Pty. Ltd. (AU) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006108212-A1 | ANTI-INFLAMMATORY MODALITIES | NOVOGEN RESEARCH PTY LTD (AU) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059176-A1 | ANTI-INFLAMMATORY MODALITIES | TNF, PTGES, NFKBIA | CYP3A4 2606/4885ALOX15 72/4885MAOB 1261/4885 |
| US-20090131513-A1 | ANTI-INFLAMMATORY MODALITIES | TNF, PTGES, NFKBIA | CYP3A4 2606/4885ALOX15 72/4885MAOB 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.