Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151329 | 0.93 | ACHE (0.53) | ACHETDP1ALDH1A1CA1CA2 | |
| Iodide SCHEMBL22027473 | 0.93 | ACHE (0.53) | ACHETDP1ALDH1A1CA1CA2 | |
| Bromide SCHEMBL1538738 | 0.93 | ACHE (0.53) | ACHETDP1ALDH1A1CA1CA2 | |
| Fluoride Ion SCHEMBL1538747 | 0.93 | ACHE (0.53) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL8511896 | 0.90 | ACHE (0.50) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL11726645 | 0.83 | ACHE (0.42) | ACHETDP1ALDH1A1CA1CA2 | |
| Benzenethiol SCHEMBL8511198 | 0.77 | ACHE (0.43) | ACHETDP1ALDH1A1CA1CA2 | |
| Phenol SCHEMBL8511587 | 0.77 | ACHE (0.43) | ACHETDP1ALDH1A1CA1CA2 | |
| P-Xylene SCHEMBL497786 | 0.73 | ACHE (0.80) | ACHETDP1ALDH1A1CA1CA2 | |
| P-Xylene SCHEMBL771 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638893-A | Polar 3, 4-isoprene rubber with self-repairing function and preparation method thereof | 东北师范大学 | 2025-03-18 | — | — | CN | claimed |
| CN-118108879-A | Supported catalyst and preparation method and application thereof | 湖南立为新材料有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118108881-A | Polypropylene with wide molecular weight distribution and preparation method thereof | 湖南立为新材料有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118108884-A | Preparation method of alpha-olefin polymer | 湖南立为新材料有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-110372813-B | Catalyst composition for preparing polyethylene wax by catalyzing ethylene polymerization and application thereof | 迈瑞尔实验设备（上海）有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-113461850-B | Trans-1, 4-poly (4, 8-2-methyl-1, 3, 7-nonane triene) and preparation method thereof | 中国科学院长春应用化学研究所 | 2022-03-29 | — | — | CN | claimed |
| CN-113999336-A | Star cis-1, 4-polyisoprene with high green strength and preparation method thereof | 中国科学院长春应用化学研究所 | 2022-02-01 | — | — | CN | claimed |
| CN-113683716-A | Ethylene polymerization catalyst, preparation method thereof and preparation method of ethylene-isobutylene copolymer | 中国石油天然气股份有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-113583158-A | Metallocene catalyst and application thereof | 中国石油天然气股份有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-112851841-B | Preparation method of polyalkyl vinyl ether | 中国科学院长春应用化学研究所 | 2021-10-12 | — | — | CN | claimed |
| CN-101397348-B | Catalytic system for isoprene or butadiene high cis-1,4- selective polymerization, preparation method and use thereof | CHANGCHUN APPLIED CHEMISTRY | 2011-02-16 | — | — | CN | claimed |
| CN-101906187-A | Application of rare earth compound with constrained geometry configuration in high-selectivity conjugated diolefin-styrene random or block copolymerization | CHANGCHUN APPLIED CHEMISTRY | 2010-12-08 | — | — | CN | claimed |
| US-20100286350-A1 | BI-COMPONENT CATALYST SYSTEM FOR ISOPRENE OR BUTADIENE CIS 1, 4-POLYMERIZATION AND POLYMERIZATION PROCESS | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2010-11-11 | — | — | US | claimed |
| CN-101704848-A | Rare earth allyl complex with constrained geometry configuration, preparation method thereof and applications thereof in conjugated diene high-cis-1, 4-selective polymerization | CHANGCHUN APPLIED CHEMISTRY | 2010-05-12 | — | — | CN | claimed |
| CN-101693754-A | Application of rare-earth complexes chelated by tridentate carbazolyl in conjugated diene and polar monomer copolymerization catalyst system | CHANGCHUN APPLIED CHEMISTRY | 2010-04-14 | — | — | CN | claimed |
| CN-101693728-A | Rare earth complex chelated by tridentate carbazolyl, preparation process of same and application of same in conjugated diene high cis-1,4 selective polymerization | CHANGCHUN APPLIED CHEMISTRY | 2010-04-14 | — | — | CN | claimed |
| CN-101475652-A | Rare earth catalyst for isoprene high cis 1,4-polymerization and preparation | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-101397348-A | Catalytic system for isoprene or butadiene high cis-1,4- selective polymerization, preparation method and use thereof | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-04-01 | — | — | CN | claimed |
| CN-101367825-A | Double-carbene clamp type rareearth complexes, preparation method and uses of the same in cis-1,4 selective polymerization of diolefin | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-02-18 | — | — | CN | claimed |
| CN-101260164-A | Syn form 1,4-selectivity polymerization catalysis system for Isoprene or butadiene and preparation method and using method | CHANGCHUN APPLIED CHEMISTRY (CN) | 2008-09-10 | — | — | CN | claimed |