Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427546 | 0.81 | TP53 (0.34) | TP53KDM4EMAOAALDH1A1 | |
| SCHEMBL15001123 | 0.75 | L3MBTL1 (0.32) | ALDH1A1 | |
| SCHEMBL14992682 | 0.75 | PDE4D (0.45) | TP53KDM4EALDH1A1CYP19A1ACHE | |
| SCHEMBL988612 | 0.73 | ACHE (0.32) | ACHE | |
| SCHEMBL15821824 | 0.72 | DRD4 (0.33) | KDM4EMAOAALDH1A1 | |
| SCHEMBL14993571 | 0.72 | ACHE (0.32) | ACHE | |
| SCHEMBL14993225 | 0.71 | ALDH1A1 (0.34) | ALDH1A1CYP19A1ACHE | |
| SCHEMBL430378 | 0.69 | MAPT (0.34) | KDM4EMAOAALDH1A1 | |
| SCHEMBL429853 | 0.68 | ACHE (0.32) | ALDH1A1ACHE | |
| SCHEMBL986617 | 0.66 | ACHE (0.35) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785181-B1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-08-17 | — | — | EP | disclosed |
| EP-2785181-B1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-08-17 | — | — | EP | disclosed |
| US-9107415-B2 | 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds, and derivatives thereof | SYNGENTA PARTICPATIONS AG (CH) | 2015-08-18 | — | — | US | disclosed |
| US-9107415-B2 | 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds, and derivatives thereof | SYNGENTA PARTICPATIONS AG (CH) | 2015-08-18 | — | — | US | disclosed |
| US-9107415-B2 | 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds, and derivatives thereof | SYNGENTA PARTICPATIONS AG (CH) | 2015-08-18 | — | — | US | disclosed |
| US-20140323303-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323303-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323303-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| EP-2785181-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | Syngenta Limited (GB) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013079708-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2013-06-06 | — | — | WO | disclosed |
| WO-2013079708-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2013-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323303-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | CNPY2, CBR3, CBR1 | TP53 4112/4885KDM4E 280/4885MAOA 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.