Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755521 | 0.84 | MAPT (0.56) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| SCHEMBL8921373 | 0.77 | HTT (0.64) | MAPTCYP1A2KMT2ALMNAMAPK1 | |
| SCHEMBL13327491 | 0.75 | MAPK1 (0.50) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| SCHEMBL13407309 | 0.74 | MAPT (0.59) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| SCHEMBL18152629 | 0.74 | HTR6 (0.49) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11240759 | 0.74 | MAPT (0.54) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| SCHEMBL16486521 | 0.74 | MAPT (0.49) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| SCHEMBL1871546 | 0.74 | MAPT (0.49) | MAPTCYP1A2KMT2ALMNAMAPK1 | |
| SCHEMBL8563517 | 0.73 | MAPT (0.61) | MAPTL3MBTL1CYP1A2KMT2ALMNA | |
| SCHEMBL12164325 | 0.73 | MAPT (0.57) | MAPTL3MBTL1CYP1A2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333103-B | Method for preparing flupirtine maleate by one-pot method | NANJING CHIA TAI TIANQING PHARMACEUTICAL CO LTD | 2015-07-22 | — | — | CN | disclosed |
| WO-2013080215-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF FLUPIRTINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ARCH PHARMALABS LIMITED (IN) | 2013-06-06 | — | — | WO | disclosed |