Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743191 | 0.84 | HTT (0.61) | HTTMAPTLMNAMAPK1HPGD | |
| SCHEMBL2572082 | 0.83 | HTT (0.50) | HTTMAPTLMNAMAPK1HPGD | |
| SCHEMBL2570948 | 0.83 | HTT (0.50) | HTTMAPTBACE1LMNAMAPK1 | |
| SCHEMBL8562887 | 0.81 | BACE1 (0.52) | HTTMAPTBACE1LMNAMAPK1 | |
| SCHEMBL8562625 | 0.78 | HTT (0.67) | HTTMAPTLMNAMAPK1HPGD | |
| SCHEMBL17175828 | 0.78 | HTT (1.00) | HTTMAPTLMNAMAPK1HPGD | |
| SCHEMBL14993458 | 0.77 | MAPT (0.60) | HTTMAPTLMNAMAPK1HPGD | |
| SCHEMBL30983987 | 0.77 | HTT (0.44) | HTTMAPTLMNAHPGDALDH1A1 | |
| SCHEMBL8561895 | 0.76 | HTT (0.52) | HTTMAPTLMNAMAPK1HPGD | |
| SCHEMBL8568952 | 0.76 | HTT (0.52) | HTTMAPTLMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |