Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212307 | 0.84 | EGFR (0.60) | MAPTEGFRKMT2APOLBRAD52 | |
| SCHEMBL8600230 | 0.82 | GSK3A (0.48) | MAPTEGFRKMT2APOLBLMNA | |
| SCHEMBL8563024 | 0.82 | KMT2A (0.57) | MAPTEGFRKMT2APOLBRAD52 | |
| SCHEMBL14423952 | 0.80 | EGFR (0.47) | MAPTEGFRKMT2APOLBLMNA | |
| SCHEMBL8598940 | 0.80 | MAPK1 (0.56) | EGFRKMT2APOLBRAD52MAPK1 | |
| SCHEMBL8569814 | 0.79 | MAPT (0.61) | MAPTEGFRKMT2APOLBRAD52 | |
| SCHEMBL8568442 | 0.79 | KDM4E (0.52) | MAPTKMT2APOLBLMNAHPGD | |
| SCHEMBL8563164 | 0.79 | MAPT (0.51) | MAPTPOLBLMNAHPGDMAPK1 | |
| SCHEMBL8122688 | 0.79 | EGFR (0.56) | MAPTEGFRKMT2APOLBRAD52 | |
| SCHEMBL8562265 | 0.77 | MAPT (0.48) | MAPTKMT2APOLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |