Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 8/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831497 | 0.86 | AKR1C3 (0.47) | AKR1C3APEX1HTTCYP2C9RXRA | |
| Methacrylic Acid SCHEMBL1562495 | 0.82 | AKR1C3 (0.43) | AKR1C3APEX1HTTCYP2C9RXRA | |
| Styrene SCHEMBL4051043 | 0.80 | AKR1C3 (0.53) | AKR1C3APEX1HTTCYP2C9KDM4E | |
| SCHEMBL14040079 | 0.77 | AKR1C3 (0.57) | AKR1C3APEX1HTTCYP2C9RXRA | |
| SCHEMBL28588058 | 0.77 | AKR1C3 (0.57) | AKR1C3APEX1HTTCYP2C9RXRA | |
| SCHEMBL208866 | 0.76 | KDM4E (0.48) | AKR1C3APEX1HTTCYP2C9RXRA | |
| SCHEMBL5885336 | 0.76 | AKR1C3 (0.38) | AKR1C3APEX1HTTKDM4E | |
| SCHEMBL8746657 | 0.76 | AKR1C3 (0.55) | AKR1C3APEX1HTTCYP2C9RXRA | |
| SCHEMBL8746654 | 0.76 | AKR1C3 (0.55) | AKR1C3APEX1HTTCYP2C9RXRA | |
| SCHEMBL2451012 | 0.75 | ALDH1A1 (0.40) | AKR1C3APEX1CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841169-A2 | HAIR PREPARATIONS COMPRISING HYDROXY-TERMINATED ORGANOPOLYSILOXANE(S) AND THICKENER(S) | Henkel AG & Co. KGaA (DE) | 2015-03-04 | — | — | EP | disclosed |
| EP-2785320-A2 | HAIR TREATMENT AGENTS CONTAINING 4-MORPHOLINO-METHYL-SUBSTITUTED SILICONE(S) AND THICKENING AGENT(S) | Henkel AG & Co. KGaA (DE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013159964-A2 | HAIR PREPARATIONS COMPRISING HYDROXY-TERMINATED ORGANOPOLYSILOXANE(S) AND THICKENER(S) | HENKEL AG & CO. KGAA (DE) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013079299-A2 | HAIR TREATMENT AGENTS CONTAINING 4-MORPHOLINO-METHYL-SUBSTITUTED SILICONE(S) AND THICKENING AGENT(S) | HENKEL AG & CO. KGAA (DE) | 2013-06-06 | — | — | WO | disclosed |