SCHEMBL14995283

SCHEMBL14995283

O=P(Oc1ccc(-c2ccccc2)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ ALDH1A1 P00352 2/20 0.44
▸ SRC P12931 1/20 0.43
▸ CA2 P00918 8/20 0.43
▸ CA1 P00915 7/20 0.43
▸ CA9 Q16790 7/20 0.43
▸ CA4 P22748 7/20 0.43
▸ CA5A P35218 7/20 0.43
▸ CA12 O43570 6/20 0.43
▸ CA7 P43166 6/20 0.43
▸ CA5B Q9Y2D0 6/20 0.43
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ PKM P14618 2/20 0.40
▸ HTT P42858 1/20 0.40
▸ CYP1A2 P05177 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9165442 0.98 L3MBTL1 (0.54) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL35394 0.91 L3MBTL1 (0.60) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL331195 0.87 L3MBTL1 (0.67) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL9163448 0.85 L3MBTL1 (0.54) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL29207963 0.85 L3MBTL1 (0.64) L3MBTL1TDP1ALDH1A1SRCCA2
Phosphine SCHEMBL28875449 0.85 L3MBTL1 (0.64) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL20710845 0.82 L3MBTL1 (0.50) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL20643973 0.82 HPGD (0.53) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL28388435 0.82 TDP1 (0.50) L3MBTL1TDP1ALDH1A1SRCCA2
SCHEMBL17491592 0.82 CYP3A4 (0.57) L3MBTL1TDP1ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10818845-B2 Organic electronic device NOVALED GMBH (DE) 2020-10-27 — — US disclosed
US-10818845-B2 Organic electronic device NOVALED GMBH (DE) 2020-10-27 — — US disclosed
US-20190312208-A1 Organic Electronic Device NOVALED GMBH (DE) 2019-10-10 — — US disclosed
US-20190312208-A1 Organic Electronic Device NOVALED GMBH (DE) 2019-10-10 — — US disclosed
US-10374165-B2 Organic electronic device NOVALED GMBH (DE) 2019-08-06 — — US disclosed
US-10374165-B2 Organic electronic device NOVALED GMBH (DE) 2019-08-06 — — US disclosed
EP-2786434-B1 ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2015-09-30 — — EP disclosed
US-20140353649-A1 Organic Electronic Device NOVALED GMBH (DE) 2014-12-04 — — US disclosed
US-20140353649-A1 Organic Electronic Device NOVALED GMBH (DE) 2014-12-04 — — US disclosed
US-20140353649-A1 Organic Electronic Device NOVALED GMBH (DE) 2014-12-04 — — US disclosed
EP-2786434-A1 ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2014-10-08 — — EP disclosed
WO-2013079678-A1 ORGANIC ELECTRONIC DEVICE NOVALED AG (DE) 2013-06-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10374165-B2 Organic electronic device SCO2, AOC2, AOC3 L3MBTL1 294/4885TDP1 3270/4885ALDH1A1 97/4885
US-10818845-B2 Organic electronic device SCO2, AOC2, AOC3 L3MBTL1 294/4885TDP1 3270/4885ALDH1A1 97/4885
US-20190312208-A1 Organic Electronic Device SCO2, AOC2, AOC3 L3MBTL1 294/4885TDP1 3270/4885ALDH1A1 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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