Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | AOC1 | P19801 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415316 | 0.81 | KDM4E (0.53) | LOXL2KDM4EMAPTLMNAGPR84 | |
| SCHEMBL3151202 | 0.79 | LOXL2 (0.38) | LOXL2KDM4EMAPTLMNAGPR84 | |
| SCHEMBL8372588 | 0.79 | GSK3A (0.40) | LOXL2KDM4EMAPTLMNAGPR84 | |
| SCHEMBL5014493 | 0.79 | LOXL2 (0.39) | LOXL2KDM4EMAPTLMNANPC1 | |
| SCHEMBL263790 | 0.77 | LOXL2 (1.00) | LOXL2KDM4EMAPTLMNANPC1 | |
| SCHEMBL3142657 | 0.76 | KDM4E (0.41) | LOXL2KDM4EMAPTLMNAGPR84 | |
| SCHEMBL12844167 | 0.76 | GRM5 (0.40) | LOXL2KDM4EMAPTLMNAGPR84 | |
| Hydrochloric Acid SCHEMBL3643761 | 0.75 | LOXL2 (0.96) | LOXL2KDM4EMAPTLMNANPC1 | |
| Hydrochloric Acid SCHEMBL1208908 | 0.75 | LOXL2 (0.96) | LOXL2KDM4EMAPTLMNANPC1 | |
| SCHEMBL31038391 | 0.75 | LOXL2 (0.74) | LOXL2DPP4KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315857-A1 | N- (4 -QUINOLINYLMETHYL) SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTHELMINTICS | E. I. DUPONT DE NEMOURS AND COMPANY | 2014-10-23 | — | — | US | disclosed |
| EP-2785694-A1 | N- (4 -QUINOLINYLMETHYL) SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTHELMINTICS | E. I. Du Pont de Nemours and Company (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013081783-A1 | N- (4 -QUINOLINYLMETHYL) SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTHELMINTICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315857-A1 | N- (4 -QUINOLINYLMETHYL) SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTHELMINTICS | NQO2, SQOR, QSOX1 | LOXL2 2936/4885DPP4 2390/4885KDM4E 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.