Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 11/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15004251 | 0.87 | MARS1 (0.46) | MARS1 | |
| SCHEMBL14995419 | 0.85 | SLC16A3 (0.41) | SLC5A1MARS1MGLLSLC16A3DYRK1A | |
| SCHEMBL14995522 | 0.81 | MARS1 (0.39) | SLC5A1MARS1DYRK1A | |
| SCHEMBL14995448 | 0.81 | SLC5A1 (0.38) | SLC5A1MARS1 | |
| SCHEMBL14995596 | 0.80 | MARS1 (0.38) | SLC5A1MARS1SLC16A3SLC16A1DYRK1A | |
| SCHEMBL14995408 | 0.79 | SLC5A1 (0.46) | SLC5A1MARS1 | |
| SCHEMBL14995489 | 0.79 | SLC16A3 (0.41) | SLC5A1MARS1SLC16A3SLC16A1DYRK1A | |
| SCHEMBL14995543 | 0.77 | RXRA (0.37) | MARS1 | |
| SCHEMBL14995587 | 0.77 | SLC5A1 (0.39) | SLC5A1MARS1DYRK1A | |
| SCHEMBL14995602 | 0.77 | SLC5A1 (0.35) | SLC5A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785705-A1 | CARBOXAMIDE-SUBSTITUTED HETEROARYL-PYRAZOLES AND THE USE THEREOF | AiCuris GmbH & Co. KG (DE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013079586-A1 | CARBOXAMIDE-SUBSTITUTED HETEROARYL-PYRAZOLES AND THE USE THEREOF | AICURIS GMBH & CO. KG (DE) | 2013-06-06 | — | — | WO | disclosed |