Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997425 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDLMNAPKMHDAC1 | |
| SCHEMBL19791859 | 0.91 | HDAC2 (0.54) | SMN1; SMN2HPGDLMNAHDAC1HDAC2 | |
| SCHEMBL8241511 | 0.84 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDLMNAPKMHDAC1 | |
| SCHEMBL6136527 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDLMNAPKMHDAC1 | |
| SCHEMBL14997395 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDLMNAPKMHDAC1 | |
| SCHEMBL6136522 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDLMNAPKMHDAC1 | |
| SCHEMBL3024846 | 0.81 | POLB (0.59) | HPGDALDH1A1KMT2A | |
| SCHEMBL3024849 | 0.81 | POLB (0.59) | HPGDALDH1A1KMT2A | |
| SCHEMBL10725495 | 0.81 | CTSB (0.57) | SMN1; SMN2HPGDLMNAPKMHDAC1 | |
| SCHEMBL12890603 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDLMNAPKMHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599767-A1 | Phenylbutyl-derivatives | Lunamed AG (CH) | 2013-06-05 | — | — | EP | disclosed |