SCHEMBL149995

SCHEMBL149995

Nc1ccc2c(c1N)Nc1ccccc1S2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.57
MAPT P10636 7/20 0.57
GAA P10253 6/20 0.57
SNCA P37840 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
BCHE P06276 2/20 0.57
ACHE P22303 2/20 0.57
ALOX15 P16050 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
CYP1A2 P05177 1/20 0.57
POLB P06746 1/20 0.57
CYP3A4 P08684 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
ALOX12 P18054 1/20 0.57
MAOA P21397 1/20 0.57
CNR1 P21554 1/20 0.57
PTGS1 P23219 1/20 0.57
SLC6A2 P23975 1/20 0.57
HTR2C P28335 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390811 1.00 NOX1 (0.57) NOX1MAPTGAASNCAMEN1
Hydrochloric Acid SCHEMBL29850528 0.98 NOX1 (0.55) NOX1MAPTGAASNCAMEN1
SCHEMBL29557697 0.88 NOX1 (0.44) NOX1MAPTGAASNCAMEN1
SCHEMBL12470797 0.88 NOX1 (0.44) NOX1MAPTGAASNCAMEN1
SCHEMBL21101750 0.84 NOX1 (0.52) NOX1MAPTGAASNCAMEN1
SCHEMBL16815268 0.84 NOX1 (0.52) NOX1MAPTGAASNCAMEN1
SCHEMBL88106 0.83 NOX1 (0.59) NOX1MAPTGAASNCAMEN1
SCHEMBL30499564 0.83 NOX1 (0.59) NOX1MAPTGAASNCAMEN1
SCHEMBL1078781 0.77 NOX1 (0.43) NOX1MAPTGAASNCAMEN1
SCHEMBL10530491 0.76 NOX1 (0.67) NOX1MAPTGAASNCAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260097043-A1 NOVEL FORMULATIONS AND VEHICLES WISTA LABORATORIES LTD. (SG) 2026-04-09 US claimed
EP-4017496-B1 FORMULATIONS FOR USE IN THE PREVENTION AND/OR TREATMENT OF PERIPHERAL NEUROPATHY AND ITS ASSOCIATED DISEASES LOH YIN SZE (SG) 2026-01-07 EP claimed
EP-4590275-A1 NOVEL FORMULATIONS AND VEHICLES WisTa Laboratories Ltd. (SG) 2025-07-30 EP claimed
US-20250222006-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2025-07-10 US claimed
CN-119947729-A Oral formulations of diaminophenothiazines and methods of making and using same in the treatment and/or prevention of disease 罗颍诗 2025-05-06 CN claimed
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2024-04-11 US claimed
WO-2024061971-A1 NOVEL FORMULATIONS AND VEHICLES WISTA LABORATORIES LTD. (SG) 2024-03-28 WO claimed
WO-2024063700-A1 ORAL FORMULATION OF DIAMINOPHENOTHIAZINES AND METHODS OF MAKING AND USING THE SAME IN THE TREATMENT AND/OR PREVENTION OF DISEASES LOH YIN SZE (SG) 2024-03-28 WO claimed
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2024-01-23 US claimed
EP-3458522-B1 PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY ICROM SPA (IT) 2024-01-03 EP claimed
CN-1496404-A Materials and methods relating to protein aggregation in neurodegenerative disease ����˹���ѧ���»� 2004-05-12 CN claimed
EP-1352077-A2 MATERIALS AND METHODS RELATING TO PROTEIN AGGREGATION IN NEURODEGENERATIVE DISEASE The University Court of The University of Aberdeen (GB) 2003-10-15 EP claimed
US-20030158204-A1 Diamino phenothiazine derivatives and composition comprising same GALEY LAURENT (FR) 2003-08-21 US claimed
CN-1436180-A Diamino phenothiazine derivs. and composition comprising same GALEY L (FR) 2003-08-13 CN claimed
EP-1311498-A1 DIAMINO PHENOTHIAZINE DERIVATIVES AND COMPOSITION COMPRISING SAME Galey, Laurent (FR) 2003-05-21 EP claimed
WO-2002055720-A9 MATERIALS AND METHODS RELATING TO PROTEIN AGGREGATION IN NEURODEGENERATIVE DISEASE UNIV ABERDEEN (GB) 2002-12-27 WO claimed
WO-2002055720-A2 MATERIALS AND METHODS RELATING TO PROTEIN AGGREGATION IN NEURODEGENERATIVE DISEASE UNIV ABERDEEN (GB) 2002-07-18 WO claimed
WO-2001096322-A1 DIAMINO PHENOTHIAZINE DERIVATIVES AND COMPOSITION COMPRISING SAME GALEY LAURENT (FR) 2001-12-20 WO claimed
US-5019496-A Photopolymerization diagnostic test composition and method for immunoassay and nucleic acid assay OSTER GERALD (US) 1991-05-28 US claimed
EP-0383126-A2 Photopolymerization diagnostic test composition and method for immunoassay and nucleic acid assay OSTER, Gerald (US) 1990-08-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222006-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885MAPT 7/4885GAA 734/4885
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885MAPT 7/4885GAA 734/4885
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds MB, TPMT, HBB NOX1 1655/4885MAPT 7/4885GAA 734/4885
US-20260097043-A1 NOVEL FORMULATIONS AND VEHICLES TPMT, PARK7, HTT NOX1 4179/4885MAPT 12/4885GAA 1174/4885
US-20030158204-A1 Diamino phenothiazine derivatives and composition comprising same TYR, IK, TH NOX1 289/4885MAPT 240/4885GAA 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.