Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 14/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895354 | 0.75 | CHRM1 (0.43) | CHRM1KDM4E | |
| SCHEMBL4894451 | 0.69 | CHRM3 (0.59) | CHRM1 | |
| SCHEMBL10576172 | 0.67 | CHRM1 (0.51) | CHRM1KDM4E | |
| SCHEMBL8585401 | 0.67 | CYP2C19 (0.49) | KDM4EKMT2A | |
| SCHEMBL8585405 | 0.67 | CYP2C19 (0.49) | KDM4EKMT2A | |
| SCHEMBL10575998 | 0.66 | HTR1A (0.52) | CHRM1KDM4E | |
| SCHEMBL9910968 | 0.65 | KCNQ2 (0.56) | CHRM1KDM4E | |
| SCHEMBL493501 | 0.65 | OPRL1 (0.39) | — | |
| SCHEMBL27225773 | 0.64 | KDM4E (0.66) | CHRM1KDM4E | |
| SCHEMBL8761642 | 0.64 | DPP7 (0.58) | CHRM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146957-B1 | QUATERNARY AMMONIUM COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE INC (US) | 2013-06-12 | — | — | EP | disclosed |