Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575998 | 0.99 | HTR1A (0.52) | CHRM1HTR1AHTR1DHTR2BHTR2A | |
| SCHEMBL8761642 | 0.84 | DPP7 (0.58) | CHRM1HTR1AHTR1DHTR2BGAA | |
| SCHEMBL9910968 | 0.83 | KCNQ2 (0.56) | CHRM1HTR1AHTR1DHTR2BGAA | |
| SCHEMBL8761484 | 0.80 | HTR1A (0.53) | CHRM1HTR1AHTR1DHTR2BGAA | |
| SCHEMBL8405067 | 0.80 | HTR1A (0.53) | CHRM1HTR1AHTR1DHTR2BGAA | |
| SCHEMBL1589765 | 0.79 | HTR1A (0.53) | CHRM1HTR1AHTR1DHTR2BGAA | |
| SCHEMBL10576544 | 0.79 | HTR2A (0.60) | CHRM1HTR2AHRH1GAAALDH1A1 | |
| SCHEMBL8655841 | 0.79 | HTR1A (0.52) | CHRM1HTR1AHTR1DHTR2BGAA | |
| SCHEMBL8761469 | 0.78 | EPHX2 (0.52) | CHRM1HTR1AHTR1DHTR2BHTR2A | |
| SCHEMBL3596195 | 0.78 | CHRM1 (0.55) | CHRM1GAAALDH1A1EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847301-A | Methods of use of α-(aminoalkyl)-arylacetic acid derivatives | PENNWALT CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| US-4783537-A | CARDIOVASCULAR DISORDERS | PENNWALT CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0222099-A2 | Alpha-(Aminoalkyl)-Arylacetic Acid Derivatives | FISONS CORPORATION (a Massachusetts corporation) (US) | 1987-05-20 | — | — | EP | disclosed |