SCHEMBL1500602

SCHEMBL1500602

O=C1c2ccc(Cl)cc2C(=O)N1c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
ESR1 P03372 3/20 0.64
CA9 Q16790 3/20 0.58
CA2 P00918 2/20 0.58
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
GFER P55789 1/20 0.50
ESR2 Q92731 1/20 0.49
S100A4 P26447 1/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
MAPT P10636 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735121 0.90 MEN1 (0.68) MEN1KMT2AESR1CA9CA2
SCHEMBL2884641 0.89 MEN1 (0.62) MEN1KMT2AESR1CA9CA2
SCHEMBL726842 0.89 KDM4E (0.59) MEN1KMT2AESR1CA9CA2
SCHEMBL9358156 0.89 ALDH1A1 (0.64) MEN1KMT2AESR1CA9CA2
SCHEMBL21258438 0.86 KMT2A (0.58) MEN1KMT2AESR1CA9CA2
SCHEMBL20490841 0.85 MEN1 (0.61) MEN1KMT2AESR1CA9CA2
SCHEMBL13323537 0.84 KMT2A (0.65) MEN1KMT2AESR1KDM4EALDH1A1
SCHEMBL3976791 0.83 MEN1 (0.53) MEN1KMT2AESR1CA9CA2
SCHEMBL9633890 0.82 CA9 (0.66) MEN1KMT2AESR1CA9CA2
SCHEMBL29710383 0.82 CA9 (0.66) MEN1KMT2AESR1CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732835-B Boron nitride-carboxylated polyarylether-polyimide composite material and preparation method thereof 吉林大学 2021-05-11 CN claimed
CN-111690262-B Heat-conducting filler grafted polyarylether-polyimide composite material and preparation method thereof 吉林大学 2021-03-30 CN claimed
CN-111732835-A Boron nitride-carboxylated polyarylether-polyimide composite material and preparation method thereof 吉林大学 2020-10-02 CN claimed
CN-111690262-A Heat-conducting filler grafted polyarylether-polyimide composite material and preparation method thereof 吉林大学 2020-09-22 CN claimed
CN-108117505-A A kind of preparation method for synthesizing diphenyl ether imidodicarbonic diamide 杜庶铭 2018-06-05 CN claimed
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
CN-102617877-B A kind of preparation method of Kapton CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2016-03-23 CN claimed
CN-105255064-A Hydrotalcite citric acid rare earth composite environment-friendly stabilizer for PVC and preparing method thereof HWASU CORP 2016-01-20 CN claimed
CN-103497337-B A kind of preparation method of Polythioetherimide NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2015-11-18 CN claimed
CN-103497337-A Preparation method of polythioetherimide NINGBO INST MATERIALS TECHNOLOGY & ENG CAS 2014-01-08 CN claimed
US-20060167216-A1 Polyethersulfone composition, method of making and articles therefrom GENERAL ELECTRIC COMPANY (US) 2006-07-27 US claimed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
EP-1660560-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
WO-2005052029-A2 POLYETHERSULFONE COMPOSITION, METHOD OF MAKING AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY (US) 2005-06-09 WO claimed
US-20050113558-A1 Polyethersulfone composition, method of making and articles therefrom GENERAL ELECTRIC COMPANY 2005-05-26 US claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
WO-2005021618-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049390-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
US-5856421-A HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1999-01-05 US claimed