Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | CFTR | P13569 | 1/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041379 | 0.93 | ABCB1 (0.71) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13881098 | 0.89 | ABCB1 (0.74) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12285238 | 0.89 | ABCB1 (0.76) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL15006531 | 0.87 | ABCB1 (0.74) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20216438 | 0.86 | ABCB1 (0.71) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL10167878 | 0.85 | ABCB1 (0.79) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL16024743 | 0.85 | ABCB1 (0.79) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20216437 | 0.85 | ABCB1 (0.70) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL268381 | 0.84 | ABCB1 (1.00) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL10040697 | 0.84 | ABCB1 (0.71) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411448-A1 | CHROMENE-4-ONE DERIVATIVES AS BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) MIMETICS | Floratek Pharma SA (CH) | 2022-12-29 | — | — | US | disclosed |
| US-20110268722-A1 | COMBINATION THERAPIES WITH MITOCHONDRIAL-TARGETED ANTI-TUMOR AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-11-03 | — | — | US | disclosed |
| US-20090099080-A1 | MITOCHONDRIA-TARGETED ANTI-TUMOR AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099080-A1 | MITOCHONDRIA-TARGETED ANTI-TUMOR AGENTS | HSPE1, TUFM, TK2 | ABCB1 1006/4885USP2 2138/4885CFTR 3445/4885 |
| US-20110268722-A1 | COMBINATION THERAPIES WITH MITOCHONDRIAL-TARGETED ANTI-TUMOR AGENTS | TFAM, AIFM1, MAVS | ABCB1 819/4885USP2 1911/4885CFTR 2607/4885 |
| US-20220411448-A1 | CHROMENE-4-ONE DERIVATIVES AS BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) MIMETICS | BDNF, NTRK2, NGF | ABCB1 1788/4885USP2 4760/4885CFTR 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.