Sugi Predict

Sugi Predict / Compounds / SCHEMBL268381

SCHEMBL268381

SCHEMBL268381

COC(=O)c1ccccc1-c1c2ccc(=N)cc-2oc2cc(N)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 1.00
▸ USP2 O75604 3/20 0.96
▸ ATM Q13315 3/20 0.96
▸ CFTR P13569 2/20 0.96
▸ PAX8 Q06710 1/20 0.96
▸ GOPC Q9HD26 1/20 0.96
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ PRKDC P78527 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.36
▸ SLC6A4 P31645 3/20 0.36
▸ SLC6A3 Q01959 3/20 0.36
▸ SLC6A2 P23975 1/20 0.36
▸ POLB P06746 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ BRAF P15056 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3808879 0.99 USP2 (0.98) ABCB1USP2ATMCFTRPAX8
Hydrochloric Acid SCHEMBL29363314 0.99 USP2 (0.98) ABCB1USP2ATMCFTRPAX8
Hydrochloric Acid SCHEMBL18816029 0.99 USP2 (0.98) ABCB1USP2ATMCFTRPAX8
SCHEMBL18872353 0.92 ABCB1 (0.85) ABCB1USP2ATMCFTRPAX8
SCHEMBL20042562 0.89 ABCB1 (0.80) ABCB1USP2ATMCFTRPAX8
SCHEMBL16024743 0.88 ABCB1 (0.79) ABCB1USP2ATMCFTRPAX8
SCHEMBL10167878 0.88 ABCB1 (0.79) ABCB1USP2ATMCFTRPAX8
SCHEMBL9979456 0.88 ABCB1 (0.79) ABCB1USP2ATMCFTRPAX8
SCHEMBL14399387 0.88 ABCB1 (0.78) ABCB1USP2ATMCFTRPAX8
SCHEMBL458205 0.87 ABCB1 (0.77) ABCB1USP2ATMCFTRPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109768151-B Multi-color LED for illumination and display and preparation method thereof 浙江大学 2020-05-08 — — CN claimed
US-8778224-B2 Fluorescent dye-siloxane hybrid resin KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-07-15 — — US claimed
US-11802211-B2 Polymeric dyes and uses thereof BECTON, DICKINSON AND COMPANY (US) 2023-10-31 — — US disclosed
US-20230176067-A1 METHODS OF CHARACTERIZING CONDENSATE-ASSOCIATED CHARACTERISTICS OF COMPOUNDS AND USES THEREOF DEWPOINT THERAPEUTICS, INC. 2023-06-08 — — US disclosed
US-20230176067-A1 METHODS OF CHARACTERIZING CONDENSATE-ASSOCIATED CHARACTERISTICS OF COMPOUNDS AND USES THEREOF DEWPOINT THERAPEUTICS, INC. 2023-06-08 — — US disclosed
US-11655504-B2 High intensity labeled reactant compositions and methods for sequencing Quantum-Si Incorporated (US) 2023-05-23 — — US disclosed
US-20210309913-A1 COMPOSITION FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2021-10-07 — — US disclosed
US-20210230428-A1 POLYMERIC DYES AND USES THEREOF BECTON DICKINSON CO (US) 2021-07-29 — — US disclosed
US-20210190775-A1 COMPOSITIONS AND METHODS FOR TAGGING AND DETECTING NUCLEIC ACIDS NANOCO TECHNOLOGIES LTD. (GB) 2021-06-24 — — US disclosed
US-10921326-B2 Fluorescent labeling of transfer RNA and study of protein synthesis THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2021-02-16 — — US disclosed
US-10921327-B2 Probes for quantitative imaging of thiols in various environments BAYLOR COLLEGE OF MEDICINE (US) 2021-02-16 — — US disclosed
WO-2002002149-A1 RHODAMINE DIAGNOSTIC AGENT AND DIAGNOSTIC METHODS FOR DETECTION OF EPITHELIAL CANCER ZILA, INC. (US) 2002-01-10 — — WO disclosed
US-20010051641-A1 MITOCHONDRIAL MEMBRANE STABILIZER DAIICHI PHARMACEUTICAL CO., LTD (JP) 2001-12-13 — — US disclosed
EP-0773794-B1 NOVEL RHODAMINE DERIVATIVES FOR PHOTODYNAMIC THERAPY OF CANCER AND IN VITRO PURGING OF THE LEUKEMIAS UNIV MONTREAL (CA) 2001-06-20 — — EP disclosed
WO-2001024824-A1 RHODAMINE DERIVATIVES FOR PHOTODYNAMIC DIAGNOSIS AND TREATMENT UNIVERSITE DE MONTREAL (CA) 2001-04-12 — — WO disclosed
EP-0953356-A1 MITOCHONDRIAL MEMBRANE STABILIZER DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-11-03 — — EP disclosed
US-5773460-A Rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias UNIVERSITE DE MONTREAL (CA) 1998-06-30 — — US disclosed
EP-0773794-A1 NOVEL RHODAMINE DERIVATIVES FOR PHOTODYNAMIC THERAPY OF CANCER AND IN VITRO PURGING OF THE LEUKEMIAS UNIVERSITE DE MONTREAL (CA) 1997-05-21 — — EP disclosed
US-5556992-A Novel rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias UNIVERSITE DE MONTREAL (CA) 1996-09-17 — — US disclosed
WO-1996007431-A1 NOVEL RHODAMINE DERIVATIVES FOR PHOTODYNAMIC THERAPY OF CANCER AND IN VITRO PURGING OF THE LEUKEMIAS UNIVERSITE DE MONTREAL (CA) 1996-03-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10921327-B2 Probes for quantitative imaging of thiols in various environments SQOR, TXN2, TXNRD1 ABCB1 2867/4885USP2 1322/4885ATM 1464/4885
US-11655504-B2 High intensity labeled reactant compositions and methods for sequencing NSUN2, FBL, DNMT3A ABCB1 3487/4885USP2 3689/4885ATM 2199/4885
US-20010051641-A1 MITOCHONDRIAL MEMBRANE STABILIZER TFAM, MDH2, NLN ABCB1 997/4885USP2 3953/4885ATM 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.