Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538473 | 0.85 | GPR119 (0.52) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL15019539 | 0.85 | GPR119 (0.52) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL22384186 | 0.84 | MEN1 (0.57) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL6538566 | 0.84 | DRD2 (0.51) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL1581964 | 0.82 | KMT2A (0.52) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL6538579 | 0.82 | TSHR (0.61) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL9797621 | 0.80 | S1PR5 (0.59) | MEN1KMT2ATP53TSHRPLA2G4B | |
| SCHEMBL9798083 | 0.80 | S1PR5 (0.59) | MEN1KMT2ATP53TSHRPLA2G4B | |
| SCHEMBL9798260 | 0.80 | S1PR5 (0.59) | MEN1KMT2ATP53TSHRPLA2G4B | |
| SCHEMBL9798246 | 0.79 | S1PR5 (0.57) | MEN1KMT2ATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | Receptos, Inc. (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014201172-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2014-12-18 | — | — | WO | disclosed |
| EP-2791112-A2 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | Receptos, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013090454-A2 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |