Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TET3 | O43151 | 2/20 | 0.52 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.52 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.52 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581919 | 0.85 | OPRM1 (0.56) | KMT2ATET3FBXL19TET1KDM2B | |
| SCHEMBL15020023 | 0.82 | DRD2 (0.53) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL5452097 | 0.81 | GAA (0.46) | KMT2ATET3FBXL19TET1KDM2B | |
| SCHEMBL16874836 | 0.80 | OPRM1 (0.59) | KMT2ATET3FBXL19TET1KDM2B | |
| SCHEMBL1581749 | 0.80 | OPRM1 (0.51) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL5468647 | 0.78 | MAPT (0.47) | KMT2ATET3FBXL19TET1KDM2B | |
| SCHEMBL1581807 | 0.78 | OPRL1 (0.58) | KMT2AALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL1581499 | 0.77 | MEN1 (0.58) | KMT2AALDH1A1KDM4EMEN1CCR1 | |
| SCHEMBL1581427 | 0.77 | OPRM1 (0.51) | CCR1SMN1; SMN2 | |
| SCHEMBL5238376 | 0.77 | MAPT (0.54) | KMT2AALDH1A1HPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |