Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15039680 | 1.00 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1THRBALOX15 | |
| SCHEMBL15020225 | 1.00 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1THRBALOX15 | |
| SCHEMBL10046785 | 0.91 | CYP3A4 (0.40) | CYP3A4TDP1ALDH1A1THRBALOX15 | |
| SCHEMBL15315668 | 0.88 | TSHR (0.41) | CYP3A4TDP1ALDH1A1THRBALOX15 | |
| SCHEMBL15019795 | 0.79 | IDO1 (0.40) | CYP3A4TDP1ALDH1A1THRBALOX15 | |
| SCHEMBL15019799 | 0.79 | IDO1 (0.40) | CYP3A4TDP1ALDH1A1THRBALOX15 | |
| SCHEMBL15020148 | 0.76 | DNM1 (0.46) | CYP3A4TDP1ALDH1A1ALOX15DNM1 | |
| SCHEMBL15020149 | 0.76 | DNM1 (0.46) | CYP3A4TDP1ALDH1A1ALOX15DNM1 | |
| SCHEMBL15039674 | 0.76 | DNM1 (0.46) | CYP3A4TDP1ALDH1A1ALOX15DNM1 | |
| SCHEMBL15020196 | 0.76 | MAPT (0.43) | CYP3A4TDP1ALDH1A1THRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791252-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |