SCHEMBL15020344

SCHEMBL15020344

C=CCNc1nnnn1C

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.40
POLB P06746 3/20 0.37
HTT P42858 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PDE7A Q13946 1/20 0.36
MAPK1 P28482 4/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GALR3 O60755 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19736455 0.66 LMNA (0.42) LMNAGAAMAPTPOLBMAPK1
SCHEMBL20095094 0.63 LMNA (0.39) LMNAGAAMAPTPOLBMAPK1
SCHEMBL11465347 0.61 ALDH1A1 (0.62) LMNAGAAPOLBHSD17B10ALDH1A1
SCHEMBL6368247 0.61
SCHEMBL8844441 0.61
SCHEMBL8843999 0.59 POLB (0.50) LMNAGAAPOLBHTTL3MBTL1
SCHEMBL31571907 0.59 ALDH1A1 (0.58) LMNAGAAHSD17B10ALDH1A1SMN1; SMN2
SCHEMBL11500115 0.58 KDM4E (0.41) LMNAGAAMAPTPOLBHTT
SCHEMBL96698 0.57
SCHEMBL3237315 0.57 GAA (0.53) GAAMAPTPOLBHTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791119-B1 N-(1,2,5-OXADIAZOL-3-YL)-, N-(1,3,4-OXADIAZOL-2-YL), N-(TETRAZOL-5-YL)- UND N-(TRIAZOL-5-YL)-ARYL CARBOXYLIC ACID AMIDES AND USE OF SAME AS HERBICIDES BAYER IP GMBH (DE) 2017-02-01 EP disclosed
US-9204650-B2 N-(1,2,5-oxadiazol-3-yl)-, N-(1,3,4-oxadiazol-2-yl)-, N-(tetrazol-5-yl)-, and N-(triazol-5-yl) aryl carboxylic acid amides and use thereof as herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-08 US disclosed
US-20140371068-A1 N-(1,2,5-OXADIAZOL-3-YL)-, N-(1,3,4-OXADIAZOL-2-YL)-, N-(TETRAZOL-5-YL)-, AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND USE THEREOF AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-12-18 US disclosed
EP-2791119-A1 N-(1,2,5-OXADIAZOL-3-YL), N-(1,3,4-OXADIAZOL-2-YL), N-(TETRAZOL-5-YL), AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND USE THEREOF AS HERBICIDES Bayer Intellectual Property GmbH (DE) 2014-10-22 EP disclosed
WO-2013087577-A1 N-(1,2,5-OXADIAZOL-3-YL), N-(1,3,4-OXADIAZOL-2-YL), N-(TETRAZOL-5-YL), AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND USE THEREOF AS HERBICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140371068-A1 N-(1,2,5-OXADIAZOL-3-YL)-, N-(1,3,4-OXADIAZOL-2-YL)-, N-(TETRAZOL-5-YL)-, AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND USE THEREOF AS HERBICIDES NAT1, MT-CO3, MT-CO1 LMNA 3322/4885GAA 1744/4885MAPT 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.