Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257396 | 0.94 | LMNA (0.40) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL15020743 | 0.94 | LMNA (0.40) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL15020549 | 0.91 | LMNA (0.42) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL15020635 | 0.91 | FPR2 (0.43) | FPR2SCN9AKCNQ3KCNQ2EGLN2 | |
| SCHEMBL15020738 | 0.91 | KMT2A (0.43) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL15020694 | 0.91 | ITGB2 (0.42) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL15020613 | 0.90 | FPR2 (0.45) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL257208 | 0.90 | FPR2 (0.45) | LMNAKMT2AFPR2SCN9AEGLN2 | |
| SCHEMBL15020638 | 0.89 | FPR2 (0.39) | LMNAKMT2AFPR2SCN9AADORA2A | |
| SCHEMBL10072360 | 0.89 | FPR2 (0.39) | LMNAKMT2AFPR2SCN9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975264-B2 | Compound acting as a cannabinoid receptor-1 inhibitor | AMOREPACIFIC CORPORATION (KR) | 2015-03-10 | — | — | US | disclosed |
| EP-2617723-A2 | NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR | Amorepacific Corporation (KR) | 2013-07-24 | — | — | EP | disclosed |
| US-20130158025-A1 | NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR | AMOREPACIFIC CORPORATION (KR) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158025-A1 | NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR | CNR1, CNR2, GPR18 | LMNA 4241/4885KMT2A 2428/4885FPR2 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.