Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17601843 | 0.83 | TSHR (0.58) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL28491623 | 0.78 | TSHR (0.51) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL28578259 | 0.76 | TSHR (0.47) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL21272 | 0.75 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL13974192 | 0.75 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL17549551 | 0.75 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL17549552 | 0.75 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL17549553 | 0.75 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL183520 | 0.74 | SIGMAR1 (0.32) | — | |
| SCHEMBL30660764 | 0.74 | TSHR (0.71) | TSHRALDH1A1TDP1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383835-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4910015-A | Crosslinked polymer of polyethylene oxide and glycidoxypropylsiloxane | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-03-20 | — | — | US | claimed |
| US-4906465-A | Antithrombogenic devices containing polysiloxanes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-03-06 | — | — | US | claimed |
| WO-1989003851-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-05-05 | — | — | WO | claimed |
| CN-115558419-A | Photocuring composite epoxy fluorosilicone resin coating and preparation method thereof and coating preparation method | 西安长峰机电研究所 | 2023-01-03 | — | — | CN | disclosed |
| CN-115536916-A | Bromine-containing composite flame retardant and application thereof | 应急管理部天津消防研究所 | 2022-12-30 | — | — | CN | disclosed |
| EP-3021948-B1 | OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS | OREAL (FR) | 2019-08-21 | — | — | EP | disclosed |
| US-20190105889-A1 | Metal Sheet Assembly having Zn-Al-Mg Coatings, an Acid Solution Application and an Adhesive | ARCELORMITTAL INVESTIGACION Y DESARROLLO, S.L. (ES) | 2019-04-11 | — | — | US | disclosed |
| EP-2859129-B1 | METHOD FOR MANUFACTURING A ZNALMG COATED SHEET COMPRISING THE APPLICATION OF AN ACID SOLUTION AND CORRESPONDING SHEET | ARCELORMITTAL (LU) | 2018-10-24 | — | — | EP | disclosed |
| WO-2016116475-A1 | O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS | L'OREAL (FR) | 2016-07-28 | — | — | WO | disclosed |
| US-20160158118-A1 | OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS | L'OREAL (FR) | 2016-06-09 | — | — | US | disclosed |
| EP-3021948-A1 | OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS | L'OREAL (FR) | 2016-05-25 | — | — | EP | disclosed |
| EP-0383835-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0383835-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4910015-A | Crosslinked polymer of polyethylene oxide and glycidoxypropylsiloxane | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-03-20 | — | — | US | disclosed |
| US-4910015-A | Crosslinked polymer of polyethylene oxide and glycidoxypropylsiloxane | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-03-20 | — | — | US | disclosed |
| US-4906465-A | Antithrombogenic devices containing polysiloxanes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4906465-A | Antithrombogenic devices containing polysiloxanes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-03-06 | — | — | US | disclosed |
| WO-1989003851-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-05-05 | — | — | WO | disclosed |
| WO-1989003851-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158118-A1 | OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS | NONO, SQLE, PFN1 | TSHR 1277/4885ALDH1A1 3851/4885TDP1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.