SCHEMBL150218

SCHEMBL150218

c1ccc(-c2cccc3c2C(c2ccccc2)c2ccccc2-3)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.44
CHRNA4 P43681 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 3/20 0.41
TP53 P04637 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
HTR2B P41595 1/20 0.41
ADRA2C P18825 2/20 0.36
PTGS2 P35354 1/20 0.36
HRH1 P35367 1/20 0.36
HTR3A P46098 1/20 0.36
PDE4D Q08499 1/20 0.36
HTR2A P28223 1/20 0.36
CYP19A1 P11511 1/20 0.36
DPP4 P27487 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30287378 1.00 CHRNB2 (0.44) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL27777789 0.90 CYP3A4 (0.41) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL27947294 0.88 MEN1 (0.42) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL27880163 0.88 KMT2A (0.46) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL28723789 0.88 CHRNB2 (0.36) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL30729576 0.88 CHRNB2 (0.36) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL29167759 0.88 ALDH1A1 (0.37) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL28881059 0.87 CHRNB2 (0.36) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL29167764 0.87 ALDH1A1 (0.48) CHRNB2CHRNA4ALDH1A1HSD17B10MAPK1
SCHEMBL31121354 0.85 MEN1 (0.38) CHRNB2CHRNA4ALDH1A1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12604655-B2 Polymer, quantum dot composition and light-emitting device employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2026-04-14 US claimed
EP-4633815-A1 A COALESCER ELEMENT WITH A TWO-LAYER ELECTRICAL INSULATION Sulzer Management AG (CH) 2025-10-22 EP claimed
CN-120082021-A Anion exchange polymer, preparation method thereof and anion exchange membrane 惠州亿纬氢能有限公司 2025-06-03 CN claimed
CN-120059724-A Double-main-body material and application thereof 吉林奥来德光电材料股份有限公司 2025-05-30 CN claimed
US-20250151606-A1 DISPLAY DEVICE AND LIGHT EMITTING COMPONENT BOE TECHNOLOGY GROUP CO., LTD. (CN) 2025-05-08 US claimed
WO-2025086726-A1 OLIGOETHER AND AMIDE SUBSTITUTED AROMATIC HYDROCARBON DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 闽都创新实验室 2025-05-01 WO claimed
CN-119841786-A Organic compound and application thereof 宁波卢米蓝新材料有限公司 2025-04-18 CN claimed
US-20250098492-A1 DISPLAY PANEL AND DISPLAY DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2025-03-20 US claimed
US-20250098525-A1 COMPOUND AND USE THEREOF IN ORGANIC OPTOELECTRONIC DEVICE SHANGHAI QUADRISTAR ELECTRONIC TECHNOLOGY CO.,LTD. (CN) 2025-03-20 US claimed
CN-119490486-A Main body material, preparation method, double-main-body organic electroluminescent material containing main body material and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2025-02-21 CN claimed
US-6589621-B1 A blend of an inorganic base, an organic base, a monofunctional organic nucleophile or a multifunctional organic nucleophile and a thermoplastic hydroxy-functionalized polyetheramine DOW GLOBAL TECHNOLOGIES INC. 2003-07-08 US claimed
EP-1144470-A3 THERMALLY STABLE POLYETHERAMINES THE DOW CHEMICAL COMPANY (US) 2002-03-13 EP claimed
CN-1331720-A Thermally stable polyetheramines DOW CHEMICAL CO (US) 2002-01-16 CN claimed
EP-1144470-A2 THERMALLY STABLE POLYETHERAMINES THE DOW CHEMICAL COMPANY (US) 2001-10-17 EP claimed
CN-1276805-A Thermally stable polyetheramines DOW CHEMICAL CO (US) 2000-12-13 CN claimed
EP-1023354-A1 THERMALLY STABLE POLYETHERAMINES THE DOW CHEMICAL COMPANY (US) 2000-08-02 EP claimed
WO-2000001750-A2 THERMALLY STABLE POLYETHERAMINES THE DOW CHEMICAL COMPANY (US) 2000-01-13 WO claimed
US-5962093-A Thermally stable polyetheramines THE DOW CHEMICAL COMPANY (US) 1999-10-05 US claimed
WO-1999020673-A1 THERMALLY STABLE POLYETHERAMINES THE DOW CHEMICAL COMPANY (US) 1999-04-29 WO claimed
US-5001281-A Isomerization of bis-phenols SHELL OIL COMPANY (US) 1991-03-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250098525-A1 COMPOUND AND USE THEREOF IN ORGANIC OPTOELECTRONIC DEVICE SLCO4C1, SLCO2A1, SLCO2B1 CHRNB2 3401/4885CHRNA4 2207/4885ALDH1A1 318/4885
US-12604655-B2 Polymer, quantum dot composition and light-emitting device employing the same RIF1, LBR, ARCN1 CHRNB2 1891/4885CHRNA4 1739/4885ALDH1A1 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.