SCHEMBL27947294

SCHEMBL27947294

Brc1ccc(-c2cccc3c2C(c2ccccc2)c2ccccc2-3)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 4/20 0.39
ALDH1A1 P00352 4/20 0.39
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
CYP1A2 P05177 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HTR2B P41595 1/20 0.35
PLK4 O00444 1/20 0.35
AURKA O14965 1/20 0.35
JAK2 O60674 1/20 0.35
LCK P06239 1/20 0.35
CDK1 P06493 1/20 0.35
CSF1R P07333 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27880163 0.94 KMT2A (0.46) MEN1KMT2ANPC1GAAMAPK1
SCHEMBL29167764 0.89 ALDH1A1 (0.48) MEN1KMT2ANPC1GAAMAPK1
SCHEMBL30287378 0.88 CHRNB2 (0.44) MAPK1ALDH1A1CHRNB2CHRNA4CYP1A2
SCHEMBL150218 0.88 CHRNB2 (0.44) MAPK1ALDH1A1CHRNB2CHRNA4CYP1A2
SCHEMBL27967593 0.86 KMT2A (0.45) MEN1KMT2ANPC1GAAMAPK1
SCHEMBL27777789 0.85 CYP3A4 (0.41) MEN1KMT2ANPC1MAPK1ALDH1A1
SCHEMBL31121354 0.84 MEN1 (0.38) MEN1KMT2ANPC1GAAMAPK1
SCHEMBL29167759 0.84 ALDH1A1 (0.37) MEN1KMT2ANPC1GAAMAPK1
SCHEMBL28723789 0.84 CHRNB2 (0.36) MAPK1ALDH1A1CHRNB2CHRNA4CYP1A2
SCHEMBL30729576 0.84 CHRNB2 (0.36) MAPK1ALDH1A1CHRNB2CHRNA4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652229-A Compound for organic optoelectronic device, and display device 三星SDI株式会社 2024-09-17 CN disclosed
CN-104946243-B Fluorene derivative, light-emitting component, luminescent device, electronic device and illuminating device 株式会社半导体能源研究所 2018-12-14 CN disclosed
CN-103477463-A Organic light-emitting element, organometallic complex, light-emitting device, electronic appliance and lighting device SEMICONDUCTOR ENERGY LAB 2013-12-25 CN disclosed