Glutamic Acid

Glutamic Acid

SCHEMBL15021996

NC(=O)CC[C@H](N)C(=O)OC[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.63
BLM P54132 1/20 0.63
PMP22 Q01453 1/20 0.63
KMT2A Q03164 1/20 0.63
GRM8 O00222 2/20 0.60
GRM6 O15303 2/20 0.60
GRM7 Q14831 2/20 0.60
GRM4 Q14833 2/20 0.60
GRIN2D O15399 1/20 0.60
GRIN3B O60391 1/20 0.60
GSR P00390 1/20 0.60
CYP1A2 P05177 1/20 0.60
GRIK1 P39086 1/20 0.60
GRM5 P41594 1/20 0.60
GRIA1 P42261 1/20 0.60
GRIA2 P42262 1/20 0.60
GRIA3 P42263 1/20 0.60
SLC1A3 P43003 1/20 0.60
SLC1A2 P43004 1/20 0.60
SLC1A1 P43005 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL7559917 0.95 ALOX15 (0.70) ALOX15BLMPMP22KMT2AGRM8
SCHEMBL1537476 0.93 ALOX15 (0.67) ALOX15BLMPMP22KMT2AGRM8
SCHEMBL5082336 0.93 ALOX15 (0.67) ALOX15BLMPMP22KMT2AGRM8
SCHEMBL1672087 0.91 GRM8 (0.65) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL2443861 0.86 PMP22 (0.86) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL9165715 0.86 PMP22 (0.86) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL9276090 0.86 PMP22 (0.86) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL1634485 0.86 PMP22 (0.86) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL352341 0.86 PMP22 (0.86) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL8429219 0.86 PMP22 (0.86) ALOX15BLMPMP22KMT2AGRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130157261-A1 Compositions and Methods for Quantitative Histology, Calibration of Images in Fluorescence Microscopy, and ddTUNEL Analyses THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) 2013-06-20 US disclosed