SCHEMBL1672087

SCHEMBL1672087

N[C@@H](COC(=O)[C@@H](N)CCC(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.65
GRM6 O15303 2/20 0.65
GRM7 Q14831 2/20 0.65
GRM4 Q14833 2/20 0.65
GRIN2D O15399 1/20 0.65
GRIN3B O60391 1/20 0.65
GSR P00390 1/20 0.65
CYP1A2 P05177 1/20 0.65
GRIK1 P39086 1/20 0.65
GRM5 P41594 1/20 0.65
GRIA1 P42261 1/20 0.65
GRIA2 P42262 1/20 0.65
GRIA3 P42263 1/20 0.65
SLC1A3 P43003 1/20 0.65
SLC1A2 P43004 1/20 0.65
SLC1A1 P43005 1/20 0.65
GRIA4 P48058 1/20 0.65
GRIN1 Q05586 1/20 0.65
GRIN2A Q12879 1/20 0.65
GRIK2 Q13002 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aspartic Acid SCHEMBL28618216 0.93 GRM8 (0.57) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL15021996 0.91 ALOX15 (0.63) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL5082336 0.86 ALOX15 (0.67) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL1537476 0.86 ALOX15 (0.67) GRM8GRM6GRM7GRM4GRIN2D
Glutamine SCHEMBL7559917 0.85 ALOX15 (0.70) GRM8GRM6GRM7GRM4GRIN2D
Isoleucine SCHEMBL29165061 0.84 CYP1A2 (0.47) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL25243676 0.83 GSR (0.44) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL45347 0.82 GABRP (0.52) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL25128372 0.82 GABRP (0.52) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL3072013 0.82 GRM8 (0.62) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10718777-B2 Combined histological stain AGILENT TECHNOLOGIES, INC. (US) 2020-07-21 US disclosed
EP-2646795-B1 METHODS FOR ANALYZING IMAGES OF SPECIMENS PROCESSED BY A PROGRAMMABLE QUANTITATIVE ASSAY DAKO DENMARK AS (DK) 2019-02-20 EP disclosed
US-10180426-B2 Quantification of single target molecules in histological samples DAKO DENMARK A/S (DK) 2019-01-15 US disclosed
US-9970874-B2 Methods and systems for analyzing images of specimens processed by a programmable quantitative assay DAKO DENMARK A/S (DK) 2018-05-15 US disclosed
US-9958449-B2 Method for enzyme-mediated signal amplification DAKO DENMARK A/S (DK) 2018-05-01 US disclosed
EP-2699691-B1 NEW METHOD FOR ENZYME-MEDIATED SIGNAL AMPLIFICATION DAKO DENMARK AS (DK) 2017-10-18 EP disclosed
US-9671400-B2 Conjugate molecules DAKO DENMARK A/S (DK) 2017-06-06 US disclosed
US-20160274122-A1 NEW METHOD FOR ENZYME-MEDIATED SIGNAL AMPLIFICATION DAKO DENMARK APS (DK) 2016-09-22 US disclosed
US-9366675-B2 Method for enzyme-mediated signal amplification DAKO DENMARK A/S (DK) 2016-06-14 US disclosed
EP-2649446-B1 COMBINED HISTOLOGICAL STAIN DAKO DENMARK AS (DK) 2016-02-24 EP disclosed
EP-2491390-A1 IMMUNOCHEMICAL DETECTION OF SINGLE TARGET ENTITIES Dako Denmark A/S (DK) 2012-08-29 EP disclosed
US-20120163681-A1 METHODS AND SYSTEMS FOR ANALYZING IMAGES OF SPECIMENS PROCESSED BY A PROGRAMMABLE QUANTITATIVE ASSAY DAKO DENMARK APS (DK) 2012-06-28 US disclosed
WO-2012076010-A1 COMBINED HISTOLOGICAL STAIN DAKO DENMARK A/S (DK) 2012-06-14 WO disclosed
WO-2012075028-A1 METHODS AND SYSTEMS FOR ANALYZING IMAGES OF SPECIMENS PROCESSED BY A PROGRAMMABLE QUANTITATIVE ASSAY DAKO DENMARK A/S (DK) 2012-06-07 WO disclosed
WO-2012062318-A1 QUANTIFICATION OF SINGLE TARGET MOLECULES IN HISTOLOGICAL SAMPLES DAKO DENMARK A/S (DK) 2012-05-18 WO disclosed
WO-2011047680-A1 IMMUNOCHEMICAL DETECTION OF SINGLE TARGET ENTITIES DAKO DENMARK A/S (DK) 2011-04-28 WO disclosed
US-20100240085-A1 CONJUGATE MOLECULES DAKO DENMARK APS (DK) 2010-09-23 US disclosed
US-20100240047-A1 METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS DAKO DENMARK APS (DK) 2010-09-23 US disclosed
WO-2010094284-A1 METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS DAKO DENMARK A/S (DK) 2010-08-26 WO disclosed
WO-2010094283-A1 CONJUGATE MOLECULES DAKO DENMARK A/S (DK) 2010-08-26 WO disclosed