SCHEMBL5082336

SCHEMBL5082336

NC(=O)CC[C@H](N)C(=O)OC[C@H](N)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.67
BLM P54132 1/20 0.67
PMP22 Q01453 1/20 0.67
KMT2A Q03164 1/20 0.67
GSR P00390 2/20 0.47
CYP1A2 P05177 2/20 0.47
SLC1A1 P43005 2/20 0.47
GRM8 O00222 1/20 0.47
GRM6 O15303 1/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIK1 P39086 1/20 0.47
GRM5 P41594 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
GRIA4 P48058 1/20 0.47
GRIN1 Q05586 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537476 1.00 ALOX15 (0.67) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL7559917 0.98 ALOX15 (0.70) ALOX15BLMPMP22KMT2AGSR
Glutamic Acid SCHEMBL15021996 0.93 ALOX15 (0.63) ALOX15BLMPMP22KMT2AGSR
Serine SCHEMBL9716102 0.92 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGSR
Valine SCHEMBL10428653 0.89 ALOX15 (0.53) ALOX15BLMPMP22KMT2AGSR
SCHEMBL1672087 0.86 GRM8 (0.65) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL10496120 0.83 KMT2A (0.59) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL9716039 0.82 ALOX15 (0.63) ALOX15BLMPMP22KMT2AGSR
SCHEMBL25243676 0.81 GSR (0.44) ALOX15BLMPMP22KMT2AGSR
Glutamine SCHEMBL5580393 0.81 KMT2A (1.00) ALOX15BLMPMP22KMT2AGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828243-A2 GROWTH HORMONE SECRETAGOGUE RECEPTOR 1A LIGANDS Gastrotech Pharma A/S (DK) 2007-09-05 EP claimed
WO-2006058539-A2 GROWTH HORMONE SECRETAGOGUE RECEPTOR 1A LIGANDS GASTROTECH PHARMA A/S (DK) 2006-06-08 WO claimed
WO-2003099322-A2 IL-11 DERIVATIVES AND THERAPEUTIC USES THEREOF ISIS INNOVATION LIMITED (GB) 2003-12-04 WO claimed
CN-110177811-B Method for protein ligation and uses thereof 奥克兰联合服务有限公司 2024-01-09 CN disclosed
US-11807671-B2 Methods for protein ligation and uses thereof AUCKLAND UNISERVICES LIMITED (NZ) 2023-11-07 US disclosed
US-20230348557-A1 T cell receptors Targeting Defective DNA Repair Proteins UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-11-02 US disclosed
EP-4099989-A2 T CELL RECEPTORS TARGETING DEFECTIVE DNA REPAIR PROTEINS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2022-12-14 EP disclosed
WO-2021158962-A2 T CELL RECEPTORS TARGETING DEFECTIVE DNA REPAIR PROTEINS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2021-08-12 WO disclosed
US-20190352343-A1 METHODS FOR PROTEIN LIGATION AND USES THEREOF AUCKLAND UNISERVICES LIMITED (NZ) 2019-11-21 US disclosed
EP-3541848-A1 METHODS FOR PROTEIN LIGATION AND USES THEREOF Auckland Uniservices Limited (NZ) 2019-09-25 EP disclosed
US-10407713-B2 Reagent usable for the isolation and/or purification of nucleic acids QIAGEN GMBH (DE) 2019-09-10 US disclosed
EP-1841445-A1 THERAPEUTIC NUTRIENT COMPOSITIONS OR COMBINATIONS AND METHODS OF THEIR USE Critical Care Connections, Inc. (CA) 2007-10-10 EP disclosed
WO-2006066404-A1 THERAPEUTIC NUTRIENT COMPOSITIONS OR COMBINATIONS AND METHODS OF THEIR USE CRITICAL CARE CONNECTIONS, INC. (CA) 2006-06-29 WO disclosed
EP-1545638-A1 CONTROLLED RELEASE THERAPEUTIC WOUND DRESSINGS Johnson & Johnson Medical Ltd. (GB) 2005-06-29 EP disclosed
US-6803203-B1 PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS BROOKHAVEN SCIENCE ASSOCIATES 2004-10-12 US disclosed
US-6803203-B1 PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS BROOKHAVEN SCIENCE ASSOCIATES 2004-10-12 US disclosed
WO-2004030712-A1 CONTROLLED RELEASE THERAPEUTIC WOUND DRESSINGS JOHNSON & JOHNSON MEDICAL LIMITED (GB) 2004-04-15 WO disclosed
US-6563025-B1 Nucleotide sequences coding enzymatic polypeptide for use in the generation of disease, pest and herbicide resistant plants BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-05-13 US disclosed
US-20020034570-A1 Cheese flavoring SYMRISE GMBH & CO. KG (DE) 2002-03-21 US disclosed
US-5965727-A NUCLEOTIDE SEQUENCE OF PROMOTER FOR ANTHRANILATE SYNTHASE GENE FROM NICOTIANA TABACUM; FOR DIRECTING TRANSCRIPTION OF DOWNSTREAM STRUCTURAL GENES BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1999-10-12 US disclosed