Stanolone

Stanolone

SCHEMBL1502216

C[C@]12CC[C@H]3[C@@H](CCC4CC(=O)CC[C@@]43C)[C@@H]1CC[C@H]2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 6/20 1.00
GPBAR1 Q8TDU6 4/20 1.00
CYP19A1 P11511 2/20 1.00
NR3C1 P04150 1/20 1.00
PGR P06401 1/20 1.00
SERPINA6 P08185 1/20 1.00
NR3C2 P08235 1/20 1.00
CYP3A4 P08684 1/20 1.00
AR P10275 1/20 1.00
HSD17B10 Q99714 1/20 1.00
MGAM O43451 1/20 1.00
AKR1B10 O60218 3/20 0.70
AKR1B1 P15121 3/20 0.70
PDK1 Q15118 2/20 0.68
PDK2 Q15119 2/20 0.68
PDK3 Q15120 2/20 0.68
PDK4 Q16654 2/20 0.68
POLB P06746 1/20 0.66
MAPK1 P28482 1/20 0.66
OR51E2 Q9H255 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stanolone SCHEMBL619535 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL3486722 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL15963544 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL24684703 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL1570704 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL24410503 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL9340073 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL333299 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL21442439 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL27379 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220206018-A1 METHODS AND SYSTEMS FOR THE DIAGNOSIS AND TREATMENT OF SEX HORMONE DISORDERS FUNCTION PROMOTING THERAPIES LLC (US) 2022-06-30 US disclosed
EP-2965085-B1 METHODS AND SYSTEMS FOR THE DIAGNOSIS AND TREATMENT OF ANDROGEN DISORDERS FUNCTION PROMOTING THERAPIES LLC (US) 2020-07-01 EP disclosed
US-20200174026-A1 METHODS AND SYSTEMS FOR THE DIAGNOSIS AND TREATMENT OF ANDROGEN DISORDERS FUNCTION PROMOTING THERAPIES LLC (US) 2020-06-04 US disclosed
US-10386375-B2 Methods and systems for the diagnosis and treatment of androgen disorders FUNCTION PROMOTING THERAPIES LLC (US) 2019-08-20 US disclosed
US-20160018420-A1 METHODS AND SYSTEMS FOR THE DIAGNOSIS AND TREATMENT OF ANDROGEN DISORDERS FUNCTION PROMOTING THERAPIES, LLC (US) 2016-01-21 US disclosed
EP-2965085-A1 METHODS AND SYSTEMS FOR THE DIAGNOSIS AND TREATMENT OF ANDROGEN DISORDERS Function Promoting Therapies, LLC (US) 2016-01-13 EP disclosed
WO-2014138026-A1 METHODS AND SYSTEMS FOR THE DIAGNOSIS AND TREATMENT OF ANDROGEN DISORDERS FUNCTION PROMOTING THERAPIES, LLC (US) 2014-09-12 WO disclosed
EP-1807118-B1 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS HARBOR BIOSCIENCES INC (US) 2014-03-12 EP disclosed
US-8586770-B2 Unsaturated steroid compounds Harbor Therapeutics, Inc. (US) 2013-11-19 US disclosed
EP-2471536-A1 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS Harbor BioSciences, Inc. (US) 2012-07-04 EP disclosed
US-20110137057-A1 Unsaturated Steroid Compounds BIOVIE INC. 2011-06-09 US disclosed
US-7910755-B2 Stem cell expansion and uses HARBOR BIOSCIENCES, INC. (US) 2011-03-22 US disclosed
EP-1807118-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS Hollis-Eden Pharmaceuticals Inc. (US) 2007-07-18 EP disclosed
US-20070077201-A1 Stem cell expansion and uses BIOVIE INC. 2007-04-05 US disclosed
US-20070014719-A1 Steroid analogs and characterization and treatment methods BIOVIE INC. 2007-01-18 US disclosed
WO-2006110172-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS HOLLIS-EDEN PHARMACEUTICALS.INC. (US) 2006-10-19 WO disclosed
WO-2000066613-A1 BONE TARGETING AGENTS FOR OSTEOPOROSIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2000-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070014719-A1 Steroid analogs and characterization and treatment methods CYP17A1, HSD17B11, HSD3B1 SHBG 40/4885GPBAR1 213/4885CYP19A1 22/4885
US-20070077201-A1 Stem cell expansion and uses NES, CD44, FGF2 SHBG 4170/4885GPBAR1 2200/4885CYP19A1 4139/4885
US-20110137057-A1 Unsaturated Steroid Compounds SREBF1, SREBF2, NR1H3 SHBG 145/4885GPBAR1 264/4885CYP19A1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.