Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 1/20 | 1.00 |
| ▸ | NR3C2 | P08235 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | AR | P10275 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | MGAM | O43451 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.70 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.68 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.68 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.68 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stanolone SCHEMBL619535 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL1502216 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL15963544 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL24684703 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL1570704 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL24410503 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL9340073 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL333299 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL21442439 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL27379 | 1.00 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458071-A1 | DIHYDROTESTOSTERONE AND DIHYDROTESTOSTERONE DERIVATIVES AND PROMOTERS IN THE TREATMENT OF CANCER | Tyme, Inc. (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201217-A1 | DIHYDROTESTOSTERONE AND DIHYDROTESTOSTERONE DERIVATIVES AND PROMOTERS IN THE TREATMENT OF CANCER | TYME, INC. (US) | 2017-11-23 | — | — | WO | disclosed |
| US-20100041631-A1 | METHODS AND AGENTS FOR TREATING TUBERCULOSIS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-02-18 | — | — | US | disclosed |
| EP-1474127-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS ANTIANDROGENIC AGENTS | ENDORECH INC (CA) | 2006-11-15 | — | — | EP | disclosed |
| US-20060025393-A1 | Steroid derivatives | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-02 | — | — | US | disclosed |
| US-6933321-B2 | For therapy of androgen-dependent diseases such as prostate cancer, benign prostatic hyperplasia, precicious puberty, polycystic ovarian syndrome, acne, hirsutism, seborrhea, androgenic alopecia and premature male baldness | ENDORECHERCHE, INC. (CA) | 2005-08-23 | — | — | US | disclosed |
| EP-1474127-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS ANTIANDROGENIC AGENTS | Endorecherche, Inc. (CA) | 2004-11-10 | — | — | EP | disclosed |
| US-20040152681-A1 | Steroid derivatives | ARCH DEVELOPMENT CORPORATION, AN ILLINOIS CORPORATION | 2004-08-05 | — | — | US | disclosed |
| US-20040006134-A1 | Antiandrogenic biphenyls | ENDORECHERCHE, INC. | 2004-01-08 | — | — | US | disclosed |
| US-6645955-B1 | Nuclear liver X receptor (LXR) and ubiquitous receptor (UR) disorders; cancer, rheumatic arthritis, diabetes, Alzheimer*s disease | ARCH DEVELOPMENT CORPORATION | 2003-11-11 | — | — | US | disclosed |
| WO-2003068217-A1 | BIPHENIL DERIVATIVES AND THEIR USE AS ANTIANDROGENIC AGENTS | ENDORECHERCHE, INC. (CA) | 2003-08-21 | — | — | WO | disclosed |
| EP-1189922-A4 | STEROID DERIVATIVES | ARCH DEV CORP (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-1189922-A1 | STEROID DERIVATIVES | Arch Development Corporation (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000066611-A1 | STEROID DERIVATIVES | ARCH DEVELOPMENT CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025393-A1 | Steroid derivatives | NR5A1, NR3C2, NR3C1 | SHBG 21/4885GPBAR1 107/4885CYP19A1 26/4885 |
| US-20040006134-A1 | Antiandrogenic biphenyls | SHBG, AR, CYP19A1 | SHBG 1/4885GPBAR1 144/4885CYP19A1 3/4885 |
| US-20040152681-A1 | Steroid derivatives | NR1H3, NR1H2, NR1H4 | SHBG 72/4885GPBAR1 21/4885CYP19A1 97/4885 |
| US-20100041631-A1 | METHODS AND AGENTS FOR TREATING TUBERCULOSIS | TKT, FNTB, ACAT1 | SHBG 705/4885GPBAR1 3126/4885CYP19A1 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.