⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706065 | 0.79 | — | — | |
| SCHEMBL235434 | 0.79 | KDM4E (0.58) | — | |
| SCHEMBL10936077 | 0.76 | KDM4E (0.55) | — | |
| SCHEMBL3519320 | 0.76 | KDM4E (0.55) | — | |
| SCHEMBL28706026 | 0.76 | KDM4E (0.55) | — | |
| Bromo Acetone SCHEMBL56383 | 0.75 | — | — | |
| SCHEMBL28634328 | 0.73 | KDM4E (0.52) | — | |
| SCHEMBL61062 | 0.73 | KDM4E (0.78) | — | |
| Bromo Acetone SCHEMBL9286851 | 0.72 | — | — | |
| Bromo Acetone SCHEMBL28874127 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114990587-B | Electrochemical synthesis method of thiazole compound | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114990587-A | Electrochemical synthesis method of thiazole compound | 华南理工大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-108727368-B | Nitrogen-containing fused heterocyclic compound, preparation method, intermediate, composition and application thereof | 上海医药集团股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-107987033-B | Application of vanillin and isomer thereof in preparation of NA inhibitor | 湖南大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-108503604-B | (4-alkyl-5-acyl-2-thiazole) hydrazone derivatives and medical application thereof | 湖南大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-108047160-B | 2- (2-benzylhydrazono) -5-acylthiazole and medical application thereof | 湖南大学 | 2020-04-03 | — | — | CN | disclosed |
| CN-108863972-A | Oxazole amide derivatives and the preparation method and application thereof | 湖南大学 | 2018-11-23 | — | — | CN | disclosed |
| US-9221739-B2 | Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-8394852-B2 | Inotilone derivatives as coherent biological response modifier (cBMR) | SAMI LABS LTD (IN) | 2013-03-12 | — | — | US | disclosed |
| EP-1370539-B1 | HIV INHIBITING N-AMINOIMIDAZOLE DERIVATIVES | LEUVEN K U RES & DEV (BE) | 2011-11-09 | — | — | EP | disclosed |
| US-7049332-B2 | HIV inhibiting N-aminoimidazole derivatives | K. U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-05-23 | — | — | US | disclosed |
| US-20040122024-A1 | Hiv inhibiting n-aminoimidazole derivatives | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2004-06-24 | — | — | US | disclosed |
| EP-1370539-A1 | HIV INHIBITING N-AMINOIMIDAZOLE DERIVATIVES | K.U. Leuven Research and Development (BE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068395-A1 | HIV INHIBITING N-AMINOIMIDAZOLE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2002-09-06 | — | — | WO | disclosed |
| EP-0372922-B1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5175309-A | Forming an imide by heat catalytic dehydration | MITSUI TOATSU CHEMICALS INC. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0372922-A2 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-13 | — | — | EP | disclosed |
| US-4309428-A | Maytansinoids | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
| EP-0025496-A1 | Maytansinoids, their production and therapeutic compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | disclosed |
| US-4206120-A | Oxaazabicycloheptane antibiotics | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |