Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309749 | 0.84 | MAPK9 (0.48) | MAPK9MAPK10MAPK8NR3C2ALDH1A1 | |
| SCHEMBL15022988 | 0.77 | MAPK9 (0.59) | MAPK9MAPK10MAPK8USP8KDM5A | |
| SCHEMBL28179494 | 0.74 | KDM5A (0.50) | MAPK9MAPK10MAPK8USP8KDM5A | |
| SCHEMBL15022076 | 0.73 | MAPK9 (0.58) | MAPK9MAPK10MAPK8USP8KDM5A | |
| SCHEMBL30273511 | 0.70 | CYP2D6 (0.51) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL8566727 | 0.70 | CYP2D6 (0.51) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL27975371 | 0.69 | MAPK9 (0.56) | MAPK9MAPK10MAPK8NR3C2ALDH1A1 | |
| SCHEMBL28078259 | 0.69 | CYP2D6 (0.50) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL10038573 | 0.67 | MDM2 (0.43) | MAPK9MAPK10MAPK8USP8MEN1 | |
| SCHEMBL15574080 | 0.66 | ALDH1A1 (0.43) | MAPK9MAPK10MAPK8KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158031-A1 | ALKYNE-BRIDGED HETERO-AROMATICS AND USES THEREOF | SU ZHOU JING HONG BIOTECH CO., LTD. (CN) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158031-A1 | ALKYNE-BRIDGED HETERO-AROMATICS AND USES THEREOF | CHRNA10, ATXN10, SCN10A | MAPK9 1943/4885MAPK10 61/4885MAPK8 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.