Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289254 | 0.87 | GRIN2D (0.51) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1502252 | 0.81 | GRIN2D (0.45) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28845737 | 0.79 | MAPT (0.46) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28334963 | 0.76 | MAPT (0.43) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28154682 | 0.76 | HTT (0.48) | MAPTSMN1; SMN2MAPK1LMNAALDH1A1 | |
| SCHEMBL28153704 | 0.76 | MAPT (0.43) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27928237 | 0.72 | MAPT (0.37) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9566694 | 0.72 | GRIN2D (0.36) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16175106 | 0.71 | TSHR (0.50) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26641103 | 0.71 | PDE10A (0.40) | MAPTGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763753-B1 | Methods for the production of 1,3,5-triamino-2,4,6-trinitrobenzene | ALLIANT TECHSYSTEMS INC. (US) | 2010-07-27 | — | — | US | claimed |
| CN-116375583-A | Preparation method of 1,3, 5-trialkoxy-2, 4, 6-trinitrobenzene | 中国科学院大连化学物理研究所 | 2023-07-04 | — | — | CN | disclosed |
| CN-116143629-A | Continuous alkylation method of trinitrophloroglucinol | 中国科学院大连化学物理研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-113527105-A | Preparation method of 1,3, 5-trialkoxy-2, 4, 6-trinitrobenzene | 四川微化盛华智能装备有限公司 | 2021-10-22 | — | — | CN | disclosed |
| US-8030521-B2 | Methods of producing 1,3,5-triamino-2,4,6-trinitrobenzene | ALLIANT TECHSYSTEMS INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-20110172463-A1 | METHODS OF PRODUCING 1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE | ALLIANT TECHSYSTEMS INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7910776-B2 | Methods of producing 1,3,5-triamino-2,4,6-trinitrobenzene | ALLIANT TECHSYSTEMS INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20100317894-A1 | METHODS OF PRODUCING 1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE | ALLIANT TECHSYSTEMS INC. (US) | 2010-12-16 | — | — | US | disclosed |
| US-7763753-B1 | Methods for the production of 1,3,5-triamino-2,4,6-trinitrobenzene | ALLIANT TECHSYSTEMS INC. (US) | 2010-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172463-A1 | METHODS OF PRODUCING 1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE | TNK1, TNS4, TDO2 | MAPT 2274/4885GRIN2D 3825/4885GRIN3B 2705/4885 |
| US-20100317894-A1 | METHODS OF PRODUCING 1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE | TST, TH, FOSB | MAPT 3121/4885GRIN2D 1545/4885GRIN3B 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.