Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536406 | 0.98 | NCEH1 (0.56) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9702459 | 0.88 | NCEH1 (0.47) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL23930399 | 0.88 | NCEH1 (0.72) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| Zinc Ion SCHEMBL536405 | 0.84 | NCEH1 (0.55) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL979842 | 0.83 | CA12 (0.58) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL8761945 | 0.82 | KDM4E (0.58) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5403782 | 0.81 | CA12 (0.56) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL12199931 | 0.81 | MAPT (0.58) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL30710587 | 0.81 | MAPT (0.58) | NCEH1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10334136 | 0.81 | NCEH1 (0.71) | NCEH1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080091043-A1 | PROCESS FOR PREPARING AN ORGANIC ACID OR ITS DERIVATIVES USING A HOMOGENEOUS MC-TYPE CATALYST AND AN O2/CO2 MIXTURE | KOCAT INC. (KR) | 2008-04-17 | — | — | US | claimed |
| EP-1911737-A1 | Process for preparing an organic acid or its derivatives using a homogeneous MC-Type catalyst an O2/CO2 mixture | Kocat Inc. (KR) | 2008-04-16 | — | — | EP | claimed |
| WO-2000027787-A1 | METHOD OF PRODUCING ACETOXYARYL CARBOXYLIC ACIDS | EASTMAN CHEMICAL COMPANY (US) | 2000-05-18 | — | — | WO | claimed |
| US-5439541-A | Combining at least one oligomer having carboxylic acid end groups with at least one oligomer having ester end groups, where at least one of the oligomers is branched; applying; curing | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1995-08-08 | — | — | US | claimed |
| US-8993799-B2 | Method for producing a purified naphthalene dicarboxylic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8780558-B2 | Porous thermoplastic foams as heat transfer materials | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8420396-B2 | For delivering DNA/RNA into cells | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8354359-B2 | Heat-sensitive adhesive agent and heat-sensitive adhesive sheet | RICOH COMPANY, LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-8324405-B2 | Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors | FIBROGEN, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120195004-A1 | Porous Thermoplastic Foams as Heat Transfer Materials | UNIVERSITY OF WASHINGTON (US) | 2012-08-02 | — | — | US | disclosed |
| WO-2011028924-A2 | POROUS THERMOPLASTIC FOAMS AS HEAT TRANSFER MATERIALS | UNIVERSITY OF WASHINGTON (US) | 2011-03-10 | — | — | WO | disclosed |
| US-20100331400-A1 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS | FIBROGEN, INC. | 2010-12-30 | — | — | US | disclosed |
| EP-0276915-A1 | Thermotropic polymer compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-03 | — | — | EP | disclosed |
| EP-0275163-A2 | Dispersion polymerisation process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-20 | — | — | EP | disclosed |
| EP-0275164-A2 | Thermotropic aromatic copolyester | HOECHST CELANESE CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |
| EP-0081900-B1 | ANISOTROPIC POLYMERS HAVING IMPROVED RETENTION OF PHYSICAL PROPERTIES AT ELEVATED TEMPERATURES AND METHODS OF MANUFACTURE THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-13 | — | — | EP | disclosed |
| EP-0188120-A2 | Moulding process | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-07-23 | — | — | EP | disclosed |
| US-4499256-A | Anisotropic polyesteramide polymers having improved retention of physical properties at elevated temperatures and methods of manufacture thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-12 | — | — | US | disclosed |
| EP-0081900-A1 | Anisotropic polymers having improved retention of physical properties at elevated temperatures and methods of manufacture thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-22 | — | — | EP | disclosed |
| US-4145443-A | HYPOTENSIVE | SYNTEX (U.S.A.) INC. (US) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331400-A1 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS | HIF1AN, HIF1A, EGLN2 | NCEH1 247/4885KDM4E 550/4885HSD17B10 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.