Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5403782 | 0.98 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23499992 | 0.89 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23499947 | 0.87 | CNR2 (0.59) | MAPTKDM4EHPGDALDH1A1CYP1A2 | |
| SCHEMBL7706394 | 0.86 | CTSD (0.60) | MAPTKDM4EHPGDALDH1A1CYP1A2 | |
| SCHEMBL3357585 | 0.86 | NCEH1 (0.65) | CA9MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL30676839 | 0.86 | NCEH1 (0.65) | CA9MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL8899727 | 0.84 | KDM4E (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10966660 | 0.84 | MAPT (0.55) | MAPTKDM4EHPGDALDH1A1CYP1A2 | |
| SCHEMBL10617741 | 0.84 | NCEH1 (0.57) | MAPTKDM4EHPGDALDH1A1CYP1A2 | |
| SCHEMBL3997233 | 0.84 | MAPT (0.55) | MAPTKDM4EHPGDALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117416983-A | Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method | 中国科学院青海盐湖研究所 | 2024-01-19 | — | — | CN | claimed |
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | claimed |
| CN-106748604-B | Method for synthesizing mono-iodo aromatic hydrocarbon or di-iodo aromatic hydrocarbon based on decarboxylation of aromatic carboxylic acid | 湘潭大学 | 2020-06-05 | — | — | CN | claimed |
| US-10191398-B2 | Electrophotographic photoconductor, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2019-01-29 | — | — | US | claimed |
| US-9738736-B2 | Combined internal donor system for Ziegler-Natta polyolefin catalysts and methods of making and using same | W. R. GRACE & CO.-CONN (US) | 2017-08-22 | — | — | US | claimed |
| US-9663595-B2 | Solid catalyst components for olefin polymerization and methods of making and using the same | W. R. Grace & Co. —Conn. (US) | 2017-05-30 | — | — | US | claimed |
| WO-2016025194-A1 | COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME | BASF CORPORATION (US) | 2016-02-18 | — | — | WO | claimed |
| US-20160046740-A1 | COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME | W. R. GRACE & CO.-CONN. | 2016-02-18 | — | — | US | claimed |
| WO-2016022421-A1 | SOLID CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION AND METHODS OF MAKING AND USING THE SAME | BASF CORPORATION (US) | 2016-02-11 | — | — | WO | claimed |
| US-20160039954-A1 | SOLID CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION AND METHODS OF MAKING AND USING THE SAME | W. R. GRACE & CO.-CONN. | 2016-02-11 | — | — | US | claimed |
| EP-1714189-A2 | UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-10-25 | — | — | EP | claimed |
| US-20060178414-A1 | Substituted biaryl amides as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2006-08-10 | — | — | US | claimed |
| EP-1487796-A4 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORP (US) | 2005-11-16 | — | — | EP | claimed |
| US-20050227168-A1 | UV radiation blocking protective layers compatible with thick film pastes | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-10-13 | — | — | US | claimed |
| WO-2005077032-A2 | UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-08-25 | — | — | WO | claimed |
| EP-1487796-A1 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-12-22 | — | — | EP | claimed |
| US-20040048913-A1 | Substituted biaryl amides as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2004-03-11 | — | — | US | claimed |
| WO-2003082826-A1 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2003-10-09 | — | — | WO | claimed |
| CN-1072930-C | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug | MCNEILAB INC (US) | 2001-10-17 | — | — | CN | claimed |
| CN-1073095-A | The compositions that contains a kind of tramadol composition and a kind of nonsteroidal anti-inflammatory drug | MCNEILAB INC (US) | 1993-06-16 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048913-A1 | Substituted biaryl amides as C5a receptor modulators | C5AR1, C5AR2, C3AR1 | CA12 4543/4885CA1 4563/4885CA2 4435/4885 |
| US-20060178414-A1 | Substituted biaryl amides as C5a receptor modulators | C5AR1, C5AR2, C3AR1 | CA12 4495/4885CA1 4586/4885CA2 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.