Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515981 | 0.82 | OPRM1 (0.49) | OPRM1OPRK1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2518903 | 0.80 | OPRM1 (0.48) | OPRM1OPRK1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2518902 | 0.80 | OPRM1 (0.48) | OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL9618251 | 0.80 | AKR1C1 (0.52) | OPRM1SLC6A2SLC6A4SLC6A3AKR1C1 | |
| SCHEMBL8434812 | 0.78 | SLC6A2 (0.52) | OPRL1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL5516837 | 0.78 | SLC6A2 (0.52) | OPRL1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL11307256 | 0.77 | OPRL1 (0.47) | OPRL1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL9066328 | 0.75 | AKR1C1 (0.46) | OPRL1OPRM1OPRK1AKR1C1 | |
| SCHEMBL15352663 | 0.74 | AKR1C1 (0.47) | SLC6A2SLC6A4SLC6A3AKR1C1 | |
| SCHEMBL2857850 | 0.70 | OPRM1 (0.45) | OPRL1OPRM1OPRK1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10160719-B2 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2018-12-25 | — | — | US | disclosed |
| US-20170137370-A1 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20120059066-A1 | PHARMACEUTICAL SALTS | GRUNENTHAL GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20050176790-A1 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176790-A1 | Pharmaceutical salts | SLC5A1, SLC5A2, SLC35A1 | OPRL1 2752/4885OPRM1 2171/4885OPRK1 1625/4885 |
| US-20120059066-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | OPRL1 2913/4885OPRM1 2283/4885OPRK1 1831/4885 |
| US-10160719-B2 | Pharmaceutical salts | SLC5A1, SLC5A2, SLC35A1 | OPRL1 2913/4885OPRM1 2283/4885OPRK1 1831/4885 |
| US-20170137370-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | OPRL1 2913/4885OPRM1 2283/4885OPRK1 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.