Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516837 | 1.00 | SLC6A2 (0.52) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| SCHEMBL11225506 | 0.84 | OPRM1 (0.47) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL8616472 | 0.82 | SLC6A4 (0.48) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| SCHEMBL11320663 | 0.82 | SLC6A4 (0.48) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| SCHEMBL11313951 | 0.81 | SLC6A4 (0.47) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| SCHEMBL2515981 | 0.81 | OPRM1 (0.49) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| SCHEMBL5242124 | 0.81 | TDP1 (0.46) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2518903 | 0.79 | OPRM1 (0.48) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL2518902 | 0.79 | OPRM1 (0.48) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL11307266 | 0.78 | KDM1A (0.47) | SLC6A2SLC6A4OPRM1SLC22A1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039742-A1 | EXTRACTION OF TRAMADOL FROM NAUCLEA LATIFOLIA SMITH | UNIVERSITE JOSEPH FOURIER - GRENOBLE 1 (FR) | 2016-02-11 | — | — | US | disclosed |
| US-5877351-A | REACTION WITH HYDROGEN BROMIDE | WYCKOFF CHEMICAL COMPANY, INC. (US) | 1999-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039742-A1 | EXTRACTION OF TRAMADOL FROM NAUCLEA LATIFOLIA SMITH | OPRK1, OPRD1, OPRM1 | SLC6A2 15/4885SLC6A4 405/4885OPRM1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.