SCHEMBL1502445

SCHEMBL1502445

Cc1cc(Br)c(O)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.58
TSHR P16473 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
CA2 P00918 2/20 0.52
CA1 P00915 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
ALDH1A1 P00352 5/20 0.52
ALOX15 P16050 2/20 0.52
ALOX12 P18054 2/20 0.52
HPGD P15428 1/20 0.52
CASP1 P29466 1/20 0.52
RECQL P46063 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
SELE P16581 1/20 0.50
TTR P02766 2/20 0.46
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL21814228 0.97 CYP3A4 (0.55) CYP3A4TSHRTDP1CA2CA1
SCHEMBL31218467 0.86 ALDH1A1 (0.52) CYP3A4TSHRTDP1CA2CA1
SCHEMBL11418582 0.86 SELL (0.65) CYP3A4TSHRTDP1CA2CA1
SCHEMBL880200 0.86 GABRA1 (0.56) CYP3A4TSHRTDP1CA2CA1
SCHEMBL2044956 0.86 ALDH1A1 (0.52) CYP3A4TSHRTDP1CA2CA1
SCHEMBL17744522 0.82 ALDH1A1 (0.60) CYP3A4TSHRTDP1CA2CA1
SCHEMBL14392219 0.82 CA2 (0.42) CYP3A4TSHRTDP1CA2CA1
SCHEMBL3298058 0.82 CHEK1 (0.55) CYP3A4TSHRTDP1CA2CA1
SCHEMBL31062998 0.82 SELL (0.46) CYP3A4TSHRTDP1CA2CA1
SCHEMBL10922054 0.82 TSHR (0.46) CYP3A4TSHRTDP1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119663540-A Fiber membrane with high-pore corrosion-resistant armored structure and preparation method and application thereof 国能神东煤炭集团有限责任公司 2025-03-21 CN claimed
CN-115368217-B Synthesis method of 3,4, 5-trimethoxytoluene 寿光永康化学工业有限公司 2024-03-15 CN claimed
CN-115368217-A Synthesis method of 3,4, 5-trimethoxytoluene 寿光永康化学工业有限公司 2022-11-22 CN claimed
CN-112898711-A Preparation method of high-strength acrylate rubber material 梁燕萍 2021-06-04 CN claimed
CN-111943823-A Preparation method of metrafenone 安徽工业大学 2020-11-17 CN claimed
CN-111793194-A Medium-low temperature latent curing epoxy resin system and preparation method thereof 北京化工大学 2020-10-20 CN claimed
CN-107954841-B Preparation method of 3, 5-dibromo-4-hydroxybenzaldehyde 天津大学 2020-09-01 CN claimed
CN-107954841-A The preparation method of one kind 3,5- dibromine-4-hydroxy benzaldehydes 天津大学 2018-04-24 CN claimed
US-9604929-B2 Functionalized carbon nanoparticles and functional polymer fibers prepared using the same KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2017-03-28 US claimed
CN-104876860-A Diaryl pyridine derivative as well as preparation method and application thereof UNIV SHANDONG 2015-09-02 CN claimed
US-6150360-A ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE JANSSEN PHARMACEUTICA N.V. (BE) 2000-11-21 US claimed
WO-1999050256-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 WO claimed
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
EP-0585887-A2 Activated metathesis catalyst system NIPPON ZEON CO., LTD. (JP) 1994-03-09 EP claimed
EP-0526651-A1 BRANCHED POLYCARBONATE IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-02-10 EP claimed
EP-0304900-A2 Strained ring cycloolefin polymer catalyst stream and process for making polymer HERCULES INCORPORATED (US) 1989-03-01 EP claimed
EP-0012939-B1 PROCESS FOR THE PRODUCTION OF 4-HYDROXYBENZALDEHYDE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-26 EP claimed
US-4218567-A Process for aromatic ethers HOFFMANN-LA ROCHE INC. (US) 1980-08-19 US claimed
EP-0012939-A1 Process for the production of 4-hydroxybenzaldehyde derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-07-09 EP claimed
US-3996291-A Process for the production of 4-hydroxy-3,5-dibromobenzaldehyde CIBA-GEIGY CORPORATION (US) 1976-12-07 US claimed