Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556512 | 0.87 | — | — | |
| SCHEMBL2449312 | 0.82 | GRM5 (0.39) | GPR119 | |
| SCHEMBL7714098 | 0.80 | MAP4K4 (0.36) | MAP4K4GPR119SETD7 | |
| SCHEMBL2576337 | 0.80 | MAP4K4 (0.36) | MAP4K4GPR119SETD7 | |
| SCHEMBL18992703 | 0.74 | SETD7 (0.38) | MAP4K4GPR119HSD17B10SETD7 | |
| SCHEMBL34461168 | 0.74 | SETD7 (0.38) | MAP4K4GPR119HSD17B10SETD7 | |
| SCHEMBL18992704 | 0.74 | SETD7 (0.38) | MAP4K4GPR119HSD17B10SETD7 | |
| SCHEMBL30582622 | 0.73 | MAP4K4 (0.36) | MAP4K4GPR119HSD17B10SETD7 | |
| SCHEMBL26537953 | 0.73 | MAP4K4 (0.36) | MAP4K4GPR119HSD17B10SETD7 | |
| SCHEMBL22126856 | 0.73 | ESR2 (0.41) | MAP4K4GPR119SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | SULT2A1, SULT1A1, SULT1E1 | MAP4K4 4175/4885GPR119 436/4885HSD17B10 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.