Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714098 | 1.00 | MAP4K4 (0.36) | MAP4K4CTSKNR1H2SETD7GPR119 | |
| SCHEMBL18992704 | 0.83 | SETD7 (0.38) | MAP4K4NR1H2SETD7GPR119UCHL1 | |
| SCHEMBL34461168 | 0.83 | SETD7 (0.38) | MAP4K4NR1H2SETD7GPR119UCHL1 | |
| SCHEMBL18992703 | 0.83 | SETD7 (0.38) | MAP4K4NR1H2SETD7GPR119UCHL1 | |
| SCHEMBL30582622 | 0.82 | MAP4K4 (0.36) | MAP4K4NR1H2SETD7GPR119HDAC1 | |
| SCHEMBL26537953 | 0.82 | MAP4K4 (0.36) | MAP4K4NR1H2SETD7GPR119HDAC1 | |
| SCHEMBL2574258 | 0.81 | GAA (0.31) | — | |
| SCHEMBL14685962 | 0.81 | GAA (0.31) | — | |
| SCHEMBL15024508 | 0.80 | MAP4K4 (0.32) | MAP4K4SETD7GPR119 | |
| SCHEMBL7714095 | 0.80 | MAP4K4 (0.35) | MAP4K4NR1H2SETD7UCHL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011125006-A2 | NOVEL SULTAM COMPOUNDS | PFIZER INC. (US) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | SULT2A1, SULT1A1, SULT1E1 | MAP4K4 4175/4885CTSK 3556/4885NR1H2 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.