Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871074 | 0.89 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL8871218 | 0.86 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| Ro-194603 SCHEMBL2464268 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL7385731 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL7385733 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL6850931 | 0.81 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL7390814 | 0.80 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL7340168 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL7394937 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2C19CYP2C9GABRA1 | |
| SCHEMBL12557206 | 0.75 | GABRA1 (0.77) | ALDH1A1CYP1A2CYP2C19GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150351-A1 | METHODS AND COMPOSITIONS FOR TREATING A SUBJECT FOR CENTRAL NERVOUS SYSTEM (CNS) INJURY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150351-A1 | METHODS AND COMPOSITIONS FOR TREATING A SUBJECT FOR CENTRAL NERVOUS SYSTEM (CNS) INJURY | GABBR2, GABBR1, GABRR3 | ALDH1A1 1701/4885CYP1A2 3157/4885CYP2C19 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.