Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138304 | 0.98 | F2 (0.43) | PDE5AAGTR1F2ELANECTSG | |
| SCHEMBL13714524 | 0.91 | F2 (0.38) | PDE5AAGTR1F2ELANECTSG | |
| SCHEMBL1610587 | 0.90 | PDE5A (0.48) | PDE5ANOTUMALDH1A1MAPTMEN1 | |
| SCHEMBL29700975 | 0.90 | PDE5A (0.48) | PDE5ANOTUMALDH1A1MAPTMEN1 | |
| SCHEMBL15025987 | 0.88 | PDE5A (0.39) | PDE5ANOTUMALDH1A1MAPTMEN1 | |
| SCHEMBL15025863 | 0.88 | APP (0.36) | PDE5AAGTR1F2ELANECTSG | |
| SCHEMBL15025986 | 0.87 | ALDH1A1 (0.39) | PDE5AAGTR1NOTUMALDH1A1MAPT | |
| SCHEMBL15025864 | 0.87 | ALDH1A1 (0.47) | PDE5ANOTUMALDH1A1MAPTMEN1 | |
| SCHEMBL10083520 | 0.87 | TP53 (0.37) | PDE5AAGTR1F2ELANECTSG | |
| SCHEMBL15025861 | 0.86 | ALDH1A1 (0.38) | PDE5AAGTR1NOTUMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981354-B2 | Organic light-emitting polymer and device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2015-03-17 | — | — | US | disclosed |
| US-20130146852-A1 | ORGANIC LIGHT-EMITTING POLYMER AND DEVICE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-06-13 | — | — | US | disclosed |