SCHEMBL1610587

SCHEMBL1610587

Cc1ccc2c(c1)Cc1cc(C)ccc1N2c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 1/20 0.48
HPGD P15428 1/20 0.44
FGFR1 P11362 1/20 0.40
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 4/20 0.39
GAA P10253 4/20 0.39
KMT2A Q03164 4/20 0.39
HSD17B10 Q99714 1/20 0.39
CASP6 P55212 1/20 0.39
TLR9 Q9NR96 1/20 0.38
OPRK1 P41145 1/20 0.38
PDE4D Q08499 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700975 1.00 PDE5A (0.48) PDE5AHPGDFGFR1MAPTNPC1
SCHEMBL15025809 0.90 PDE5A (0.41) PDE5AMAPTKDM4EALDH1A1MEN1
SCHEMBL13138304 0.89 F2 (0.43) PDE5AMAPTNPC1RAB9AALDH1A1
SCHEMBL11965824 0.87 L3MBTL1 (0.51) PDE5AMAPTALDH1A1MEN1GAA
SCHEMBL13911846 0.87 PDE5A (0.39) PDE5AHPGDFGFR1MAPTNPC1
SCHEMBL2343941 0.86 HPGD (0.65) PDE5AHPGDMAPTKDM4EALDH1A1
SCHEMBL14155275 0.84 HPGD (0.45) PDE5AHPGDFGFR1MAPTNPC1
SCHEMBL12901974 0.84 HPGD (0.53) PDE5AHPGDFGFR1MAPTNPC1
SCHEMBL13828496 0.84 PDE5A (0.38) PDE5AHPGDFGFR1MAPTRAB9A
SCHEMBL18943508 0.83 KMT2A (0.47) PDE5AHPGDMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134165-A1 COMPOSITION AND LIGHT EMITTING DEVICE CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-04 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND CCNE2, C1S, SCO2 PDE5A 4686/4885HPGD 3413/4885FGFR1 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.