Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610587 | 1.00 | PDE5A (0.48) | PDE5AHPGDFGFR1MAPTNPC1 | |
| SCHEMBL15025809 | 0.90 | PDE5A (0.41) | PDE5AMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL13138304 | 0.89 | F2 (0.43) | PDE5AMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11965824 | 0.87 | L3MBTL1 (0.51) | PDE5AMAPTALDH1A1MEN1GAA | |
| SCHEMBL13911846 | 0.87 | PDE5A (0.39) | PDE5AHPGDFGFR1MAPTNPC1 | |
| SCHEMBL2343941 | 0.86 | HPGD (0.65) | PDE5AHPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL14155275 | 0.84 | HPGD (0.45) | PDE5AHPGDFGFR1MAPTNPC1 | |
| SCHEMBL12901974 | 0.84 | HPGD (0.53) | PDE5AHPGDFGFR1MAPTNPC1 | |
| SCHEMBL13828496 | 0.84 | PDE5A (0.38) | PDE5AHPGDFGFR1MAPTRAB9A | |
| SCHEMBL18943508 | 0.83 | KMT2A (0.47) | PDE5AHPGDMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685333-A | Synthetic method of tiamulin and intermediate thereof | 广州自远生物科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685330-A | Process for producing mercaptoethylene compound | 华南理工大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685331-A | Process for producing 1, 2-dithioethane compound | 华南理工大学 | 2022-07-01 | — | — | CN | disclosed |