SCHEMBL15025832

SCHEMBL15025832

Cc1ccc(CCCCc2ccc(-c3nc(-c4ccc(C)cc4)nc(-c4ccc(CCCCc5ccc(C)cc5)cc4)n3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
IGF1R P08069 1/20 0.48
ALOX15 P16050 1/20 0.48
CYP1A2 P05177 2/20 0.45
CYP2A6 P11509 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
RAB9A P51151 5/20 0.45
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HRH1 P35367 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15025746 0.98 ATM (0.50) ATMTDP1L3MBTL1IGF1RALOX15
SCHEMBL15025998 0.98 ATM (0.50) ATMTDP1L3MBTL1IGF1RALOX15
SCHEMBL15025717 0.91 L3MBTL1 (0.46) ATMTDP1L3MBTL1IGF1RALOX15
SCHEMBL11976539 0.91 ALDH1A1 (0.58) ATMRAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL11927622 0.91 ALDH1A1 (0.58) ATMRAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL12374397 0.90 RAB9A (0.51) ATMTDP1L3MBTL1RAB9AALDH1A1
SCHEMBL15281175 0.89 ALDH1A1 (0.56) ATMRAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL15281188 0.89 ALDH1A1 (0.56) ATMRAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL15281182 0.89 ALDH1A1 (0.56) ATMRAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL15760687 0.89 ALDH1A1 (0.56) ATMRAB9AALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8981354-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-20130146852-A1 ORGANIC LIGHT-EMITTING POLYMER AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-06-13 US disclosed